Innovative design of targeted nanoparticles: polymer–drug conjugates for enhanced cancer therapy

VB Junyaprasert, P Thummarati - Pharmaceutics, 2023 - mdpi.com
Polymer–drug conjugates (PDCs) have shown great promise in enhancing the efficacy and
safety of cancer therapy. These conjugates combine the advantageous properties of both …

Ligand-targeted delivery of photosensitizers for cancer treatment

P Gierlich, AI Mata, C Donohoe, RMM Brito, MO Senge… - Molecules, 2020 - mdpi.com
Photodynamic therapy (PDT) is a promising cancer treatment which involves a
photosensitizer (PS), light at a specific wavelength for PS activation and oxygen, which …

[HTML][HTML] Nanotheranostics: emerging strategies for early diagnosis and therapy of brain cancer

MK Viswanadh, RP Singh, P Agrawal… - …, 2018 - ncbi.nlm.nih.gov
Nanotheranostics have demonstrated the development of advanced platforms that can
diagnose brain cancer at early stages, initiate first-line therapy, monitor it, and if needed …

Bioadhesive chitosan nanoparticles: dual targeting and pharmacokinetic aspects for advanced lung cancer treatment

MK Viswanadh, AK Mehata, V Sharma, V Priya… - Carbohydrate …, 2021 - Elsevier
The chitosan-folate conjugate was synthesized initially and confirmed by FTIR and NMR
spectroscopic studies. Following, docetaxel (DXL) loaded non-targeted, single receptor and …

RGD-decorated PLGA nanoparticles improved effectiveness and safety of cisplatin for lung cancer therapy

B Yadav, M Chauhan, S Shekhar, A Kumar… - International Journal of …, 2023 - Elsevier
Upon extensive pharmaceutical and biomedical research to treat lung cancer indicates that
lung cancer remains one of the deadliest diseases and the leading cause of death in men …

Trastuzumab decorated TPGS-g-chitosan nanoparticles for targeted breast cancer therapy

AK Mehata, S Bharti, P Singh, MK Viswanadh… - Colloids and Surfaces B …, 2019 - Elsevier
Breast cancer, up-regulated with human epidermal growth factor receptor type-2 (HER-2)
has led to the concept of developing HER-2 targeted anticancer therapeutics. Docetaxel …

Clinical applications of nanomedicines in lung cancer treatment

M Norouzi, P Hardy - Acta biomaterialia, 2021 - Elsevier
Lung cancer is the leading cause of cancer mortality worldwide. Owing to a lack of early-
stage diagnosis, most lung cancers are detected in advanced stages, limiting the available …

TPGS-chitosan cross-linked targeted nanoparticles for effective brain cancer therapy

P Agrawal, RP Singh, L Kumari, G Sharma… - Materials science and …, 2017 - Elsevier
Brain cancer, up-regulated with transferrin receptor led to concept of transferrin receptor
targeted anticancer therapeutics. Docetaxel loaded d-α-tocopherol polyethylene glycol 1000 …

Recent advances in TPGS-based nanoparticles of docetaxel for improved chemotherapy

H Choudhury, B Gorain, M Pandey, SA Kumbhar… - International journal of …, 2017 - Elsevier
Docetaxel (DTX) is one of the important antitumor drugs, being used in several common
chemotherapies to control leading cancer types. Severe toxicities of the DTX are prominent …

Transferrin liposomes of docetaxel for brain-targeted cancer applications: formulation and brain theranostics

Sonali, RP Singh, N Singh, G Sharma… - Drug …, 2016 - Taylor & Francis
Diagnosis and therapy of brain cancer was often limited due to low permeability of delivery
materials across the blood–brain barrier (BBB) and their poor penetration into the brain …