Pharmacologic treatment of primary osteoporosis or low bone mass to prevent fractures in adults: a living clinical guideline from the American College of Physicians

A Qaseem, LA Hicks… - Annals of internal …, 2023 - acpjournals.org
An update is available for this article. Description: This guideline updates the 2017 American
College of Physicians (ACP) recommendations on pharmacologic treatment of primary …

[HTML][HTML] Efficacy of antiresorptive treatment in osteoporotic older adults: a systematic review and meta-analysis of randomized clinical trials

BA Cedeno-Veloz, JE Lopez… - The Journal of nutrition …, 2022 - Elsevier
Objectives To investigate concerns surrounding the benefits of antiresorptive drugs in older
adults, a systematic review was carried out to evaluate the efficacy of these treatments in the …

Large-scale circulating proteome association study (CPAS) meta-analysis identifies circulating proteins and pathways predicting incident hip fractures

TR Austin, HA Fink, DI Jalal, AE Törnqvist… - Journal of Bone and …, 2024 - academic.oup.com
Hip fractures are associated with significant disability, high cost, and mortality. However, the
exact biological mechanisms underlying susceptibility to hip fractures remain incompletely …

Mortality risk after the first occurrence of osteoporotic vertebral compression fractures in the general population: A nationwide cohort study

HJ Son, SJ Park, JK Kim, JS Park - PLoS One, 2023 - journals.plos.org
Osteoporotic vertebral compression fractures (OVCF) can cause severe pain, changes in
balance, gait velocity, muscle fatigue, risk of falls, and subsequent fractures. Thus, OVCF …

Disparities in management of symptomatic osteoporotic vertebral compression fractures: a nationwide multidisciplinary survey

A Weber, TFG Vercoulen, E Jacobs, AT Buizer… - Archives of …, 2024 - Springer
This nationwide multidisciplinary survey found dissatisfaction among physicians with current
osteoporotic vertebral compression fracture care, revealing significant disparities in …

[HTML][HTML] Refracture risk and all-cause mortality after vertebral fragility fractures: Anti-osteoporotic medications matter

TW Tai, YL Tsai, CA Shih, CC Li, YF Chang… - Journal of the Formosan …, 2023 - Elsevier
Background Osteoporotic vertebral fractures may predict the future occurrence of fractures
and increase mortality. Treating underlying osteoporosis may prevent second fractures …

A plasma protein-based risk score to predict hip fractures

TR Austin, M Nethander, HA Fink, AE Törnqvist… - Nature aging, 2024 - nature.com
As there are effective treatments to reduce hip fractures, identification of patients at high risk
of hip fracture is important to inform efficient intervention strategies. To obtain a new tool for …

Insufficient increase in bone mineral density testing rates and pharmacotherapy after hip and vertebral fracture: analysis of the National Database of Health Insurance …

S Nakatoh, K Fujimori, S Ishii, J Tamaki… - Archives of …, 2021 - Springer
Test and treatment rates for osteoporosis in Japan aimed at preventing secondary fragility
fractures were insufficient. Those who suffered hip fractures had approximately half the rates …

The current situation in the approach to osteoporosis in older adults in Turkey: areas in need of improvement with a model for other populations

G Bahat, NM Catikkas, DG Yavuz, P Borman… - Archives of …, 2021 - Springer
Purpose The total number of older adults in Turkey is striking, amounting to around 8 million,
and this translates into considerably higher numbers of cases of osteoporosis (OP) and …

Phantomless calibration of CT scans for hip fracture risk prediction in silico: Comparison with phantom-based calibration

JA Szyszko, A Aldieri, AA La Mattina, M Viceconti - PloS one, 2024 - journals.plos.org
Finite element models built from quantitative computed tomography images rely on element-
wise mapping of material properties starting from Hounsfield Units (HU), which can be …