Sedentary behavior and cancer–an umbrella review and meta-analysis

R Hermelink, MF Leitzmann, G Markozannes… - European Journal of …, 2022 - Springer
Several systematic reviews and meta-analyses have summarized the association between
sedentary behavior (SB) and cancer. However, the level of evidence and the potential for …

Obesity and main urologic cancers: Current systematic evidence, novel biological mechanisms, perspectives and challenges

G Papavasileiou, D Tsilingiris, N Spyrou… - Seminars in Cancer …, 2023 - Elsevier
Urologic cancers (UC) account for 13.1% of all new cancer cases and 7.9% of all cancer-
related deaths. A growing body of evidence has indicated a potential causal link between …

Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries

C Fernandez-Rozadilla, M Timofeeva, Z Chen, P Law… - Nature …, 2023 - nature.com
Colorectal cancer (CRC) is a leading cause of mortality worldwide. We conducted a genome-
wide association study meta-analysis of 100,204 CRC cases and 154,587 controls of …

Ultra-processed food consumption, cancer risk and cancer mortality: a large-scale prospective analysis within the UK Biobank

K Chang, MJ Gunter, F Rauber, RB Levy… - …, 2023 - thelancet.com
Background Global dietary patterns are increasingly dominated by relatively cheap, highly
palatable, and ready-to-eat ultra-processed foods (UPFs). However, prospective evidence is …

Gastrointestinal consequences of type 2 diabetes mellitus and impaired glycemic homeostasis: a mendelian randomization study

J Chen, S Yuan, T Fu, X Ruan, J Qiao, X Wang… - Diabetes …, 2023 - Am Diabetes Assoc
OBJECTIVE We conducted a Mendelian randomization (MR) study to examine the
associations of type 2 diabetes and glycemic traits with gastrointestinal diseases (GDs) …

Variations in comorbidity burden in people with type 2 diabetes over disease duration: A population-based analysis of real world evidence

J Pearson-Stuttard, S Holloway, R Polya, R Sloan… - …, 2022 - thelancet.com
Background The prevalence of type 2 diabetes (T2DM) is increasing, but increasing
longevity among persons with diagnosed diabetes may be is associated with more …

Association between age at diabetes onset or diabetes duration and subsequent risk of pancreatic cancer: results from a longitudinal cohort and mendelian …

B Shen, Y Li, CS Sheng, L Liu, T Hou, N Xia… - The Lancet Regional …, 2023 - thelancet.com
Background The aim of the study is to estimate the incidence of pancreatic cancer among
individuals with new-onset type 2 Diabetes (T2DM) and evaluate the relationship of …

Atherosclerosis, diabetes mellitus, and cancer: common epidemiology, shared mechanisms, and future management

V Katsi, I Papakonstantinou, K Tsioufis - International Journal of …, 2023 - mdpi.com
The involvement of cardiovascular disease in cancer onset and development represents a
contemporary interest in basic science. It has been recognized, from the most recent …

Incident early-and later-onset type 2 diabetes and risk of early-and later-onset cancer: prospective cohort study

Y Zhang, M Song, Y Cao, AH Eliassen… - Diabetes …, 2023 - Am Diabetes Assoc
OBJECTIVE We evaluated prospectively the association between incident early-onset
(diagnosed before 40 years of age) and later-onset type 2 diabetes and early-onset …

How far beyond diabetes can the benefits of glucagon-like peptide-1 receptor agonists go? A review of the evidence on their effects on hepatocellular carcinoma

K Arvanitakis, T Koufakis, K Kotsa, G Germanidis - Cancers, 2022 - mdpi.com
Simple Summary Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) were drugs
originally intended for the management of diabetes, while their role on the treatment of …