[HTML][HTML] MicroRNAs: new biomarkers for diagnosis, prognosis, therapy prediction and therapeutic tools for breast cancer

G Bertoli, C Cava, I Castiglioni - Theranostics, 2015 - ncbi.nlm.nih.gov
Dysregulation of microRNAs (miRNAs) is involved in the initiation and progression of
several human cancers, including breast cancer (BC), as strong evidence has been found …

A review of computational tools in microRNA discovery

CPC Gomes, JH Cho, L Hood, OL Franco… - Frontiers in …, 2013 - frontiersin.org
Since microRNAs (miRNAs) were discovered, their impact on regulating various biological
activities has been a surprising and exciting field. Knowing the entire repertoire of these …

Deep neural architectures for highly imbalanced data in bioinformatics

LA Bugnon, C Yones, DH Milone… - IEEE Transactions on …, 2019 - ieeexplore.ieee.org
In the postgenome era, many problems in bioinformatics have arisen due to the generation
of large amounts of imbalanced data. In particular, the computational classification of …

[HTML][HTML] Genome-wide computational prediction of miRNAs in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) revealed target genes involved in …

S Saini, A Saini, CJ Thakur, V Kumar… - Molecular Biology …, 2020 - ncbi.nlm.nih.gov
The current outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in
China threatened humankind worldwide. The coronaviruses contains the largest RNA …

Predicting novel microRNA: a comprehensive comparison of machine learning approaches

G Stegmayer, LE Di Persia, M Rubiolo… - Briefings in …, 2019 - academic.oup.com
Motivation The importance of microRNAs (miRNAs) is widely recognized in the community
nowadays because these short segments of RNA can play several roles in almost all …

Robust and efficient COVID-19 detection techniques: A machine learning approach

MM Hasan, SB Murtaz, MU Islam, MJ Sadeq, J Uddin - PLoS One, 2022 - journals.plos.org
The devastating impact of the Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-
CoV-2) pandemic almost halted the global economy and is responsible for 6 million deaths …

Integrating genetics and epigenetics in breast cancer: biological insights, experimental, computational methods and therapeutic potential

C Cava, G Bertoli, I Castiglioni - BMC systems biology, 2015 - Springer
Background Development of human cancer can proceed through the accumulation of
different genetic changes affecting the structure and function of the genome. Combined …

[HTML][HTML] Deep Learning for the discovery of new pre-miRNAs: Helping the fight against COVID-19

LA Bugnon, J Raad, GA Merino, C Yones, F Ariel… - Machine Learning with …, 2021 - Elsevier
Abstract The Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) has been
recently found responsible for the pandemic outbreak of a novel coronavirus disease …

Hybrid deep neural network for handling data imbalance in precursor MicroRNA

DK Jain, K Kotecha, S Pandya, SS Reddy, RE… - Frontiers in Public …, 2021 - frontiersin.org
Over the last decade, the field of bioinformatics has been increasing rapidly. Robust
bioinformatics tools are going to play a vital role in future progress. Scientists working in the …

Hepatitis B Virus and microRNAs: A Bioinformatics Approach

V Zulian, G Fiscon, P Paci, AR Garbuglia - International Journal of …, 2023 - mdpi.com
In recent decades, microRNAs (miRNAs) have emerged as key regulators of gene
expression, and the identification of viral miRNAs (v-miRNAs) within some viruses, including …