Preclinical studies of the T cell growth factor activity of IL-2 resulted in this cytokine
becoming the first immunotherapy to be approved nearly 30 years ago by the US Food and …

Abstract Interleukin-2 (IL-2) and its receptor (IL-2R) are essential in orchestrating immune
responses. Their function and expression in the tumor microenvironment make them …

Monoclonal antibody (mAb) therapy has successfully been introduced as treatment of
several lymphomas and leukemias. However, solid tumors reduce the efficacy of mAb …

Highly pathogenic virus infections usually trigger cytokine storms, which may have adverse
effects on vital organs and result in high mortalities. The two cytokines interleukin (IL)-4 and …

Background Post-acute coronavirus disease 2019 (COVID-19) syndrome, also known as
long COVID, is a prolonged illness after the acute phase of COVID-19. Hospitalized patients …

Traditional Chinese medicine (TCM) had demonstrated effectiveness in the prevention and
control of COVID-19. Statistics showed that Ephedra and Glycyrrhiza were frequently used in …

A water-soluble polysaccharide (BP-1) was extracted and purified from highland barley
(Hordeum vulgare L.) and its average molecular weight was about 6.7× 104 Da. In this …

Introduction: Major depressive disorder (MDD) can impact the severity of allergic rhinitis
(AR) and asthma (AA). Here, we evaluated the cytokine production by T-cells from AR and …

Cerebral vasospasm (VSP) is a common phenomenon after aneurysmal subarachnoid
hemorrhage (aSAH) and contributes to neurocognitive decline. The natural history of the pro …

Past researches indicate that some types of antibiotics, apart from their antimicrobial effects,
have some other important effects which indirectly are exerted by modulating and regulating …