Consensus on diagnosis and management of Cushing's disease: a guideline update

M Fleseriu, R Auchus, I Bancos… - The lancet Diabetes & …, 2021 - thelancet.com
Cushing's disease requires accurate diagnosis, careful treatment selection, and long-term
management to optimise patient outcomes. The Pituitary Society convened a consensus …

DXA parameters, Trabecular Bone Score (TBS) and Bone Mineral Density (BMD), in fracture risk prediction in endocrine-mediated secondary osteoporosis

E Shevroja, FP Cafarelli, G Guglielmi, D Hans - Endocrine, 2021 - Springer
Osteoporosis, a disease characterized by low bone mass and alterations of bone
microarchitecture, leading to an increased risk for fragility fractures and, eventually, to …

Efficacy and safety of osilodrostat in patients with Cushing's disease (LINC 3): a multicentre phase III study with a double-blind, randomised withdrawal phase

R Pivonello, M Fleseriu, J Newell-Price… - The Lancet Diabetes & …, 2020 - thelancet.com
Background Cushing's disease is a rare endocrine disorder characterised by cortisol
overproduction with severe complications. Therapies for cortisol reduction are often …

Complications of Cushing's syndrome: state of the art

R Pivonello, AM Isidori, MC De Martino… - The lancet Diabetes & …, 2016 - thelancet.com
Cushing's syndrome is a serious endocrine disease caused by chronic, autonomous, and
excessive secretion of cortisol. The syndrome is associated with increased mortality and …

Lipid management in patients with endocrine disorders: an endocrine society clinical practice guideline

CB Newman, MJ Blaha, JB Boord… - The Journal of …, 2020 - academic.oup.com
Objective This guideline will provide the practicing endocrinologist with an approach to the
assessment and treatment of dyslipidemia in patients with endocrine diseases, with the …

Medical treatment of Cushing's disease: an overview of the current and recent clinical trials

R Pivonello, R Ferrigno, MC De Martino… - Frontiers in …, 2020 - frontiersin.org
Cushing's disease (CD) is a serious endocrine disorder characterized by chronic
hypercortisolism, or Cushing's syndrome (CS), caused by a corticotroph pituitary tumor …

Clinical, pathophysiologic, genetic, and therapeutic progress in primary bilateral macronodular adrenal hyperplasia

J Bertherat, I Bourdeau, L Bouys… - Endocrine …, 2023 - academic.oup.com
Patients with primary bilateral macronodular adrenal hyperplasia (PBMAH) usually present
bilateral benign adrenocortical macronodules at imaging and variable levels of cortisol …

Cushing syndrome: a review

M Reincke, M Fleseriu - Jama, 2023 - jamanetwork.com
Importance Cushing syndrome is defined as a prolonged increase in plasma cortisol levels
that is not due to a physiological etiology. Although the most frequent cause of Cushing …

Mortality in patients with Cushing's disease more than 10 years after remission: a multicentre, multinational, retrospective cohort study

RN Clayton, PW Jones, RC Reulen… - The lancet Diabetes & …, 2016 - thelancet.com
Background No agreement has been reached on the long-term survival prospects for
patients with Cushing's disease. We studied life expectancy in patients who had received …

The hypothalamus for whole-body physiology: from metabolism to aging

T Liu, Y Xu, CX Yi, Q Tong, D Cai - Protein & Cell, 2022 - academic.oup.com
Obesity and aging are two important epidemic factors for metabolic syndrome and many
other health issues, which contribute to devastating diseases such as cardiovascular …