Carbohydrate-active enzymes (CAZymes) in the gut microbiome

JF Wardman, RK Bains, P Rahfeld… - Nature Reviews …, 2022 - nature.com
The 1013–1014 microorganisms present in the human gut (collectively known as the human
gut microbiota) dedicate substantial percentages of their genomes to the degradation and …

Polysaccharide utilization loci: fueling microbial communities

JM Grondin, K Tamura, G Déjean, DW Abbott… - Journal of …, 2017 - Am Soc Microbiol
The complex carbohydrates of terrestrial and marine biomass represent a rich nutrient
source for free-living and mutualistic microbes alike. The enzymatic saccharification of these …

Bacteroidetes use thousands of enzyme combinations to break down glycans

P Lapébie, V Lombard, E Drula, N Terrapon… - Nature …, 2019 - nature.com
Unlike proteins, glycan chains are not directly encoded by DNA, but by the specificity of the
enzymes that assemble them. Theoretical calculations have proposed an astronomical …

PULDB: the expanded database of polysaccharide utilization loci

N Terrapon, V Lombard, E Drula, P Lapébie… - Nucleic acids …, 2018 - academic.oup.com
Abstract The Polysaccharide Utilization Loci (PUL) database was launched in 2015 to
present PUL predictions in∼ 70 Bacteroidetes species isolated from the human …

Gut microbiota development in the growing dog: A dynamic process influenced by maternal, environmental and host factors

Q Garrigues, E Apper, S Chastant… - Frontiers in Veterinary …, 2022 - frontiersin.org
Microorganisms of the gastrointestinal tract play a crucial role in the health, metabolism and
development of their host by modulating vital functions such as digestion, production of key …

A Marine Group A isolate relies on other growing bacteria for cell wall formation

T Katayama, MK Nobu, H Imachi, N Hosogi… - Nature …, 2024 - nature.com
Most of Earth's prokaryotes live under energy limitation, yet the full breadth of strategies that
enable survival under such conditions remain poorly understood. Here we report the …

Non-oral Prevotella stepping into the spotlight

T Accetto, G Avguštin - Anaerobe, 2021 - Elsevier
Species now affiliated to genus Prevotella have been known for decades as an integral part
of human oral cavity microbiota. They were frequently isolated from patients with …

Novel xylan-degrading enzymes from polysaccharide utilizing loci of Prevotella copri DSM18205

JA Linares-Pastén, JS Hero, JH Pisa, C Teixeira… - …, 2021 - academic.oup.com
Prevotella copri is a bacterium that can be found in the human gastrointestinal tract (GIT).
The role of P. copri in the GIT is unclear, and elevated numbers of the microbe have been …

[HTML][HTML] Peptidoglycan salvage enables the periodontal pathogen Tannerella forsythia to survive within the oral microbial community

I Hottmann, M Borisova, C Schäffer, C Mayer - Microbial Physiology, 2021 - karger.com
Tannerella forsythia is an anaerobic, fusiform Gram-negative oral pathogen strongly
associated with periodontitis, a multibacterial inflammatory disease that leads to the …

Compendium of 5810 genomes of sheep and goat gut microbiomes provides new insights into the glycan and mucin utilization

K Zhang, C He, L Wang, L Suo, M Guo, J Guo, T Zhang… - Microbiome, 2024 - Springer
Background Ruminant gut microbiota are critical in ecological adaptation, evolution, and
nutrition utilization because it regulates energy metabolism, promotes nutrient absorption …