RNA methylations, as the prevalent post-transcriptional modifications, are critical in
regulating various biological processes, such as RNA transcription, splicing, structure …

The importance of noise exposure as a major environmental determinant of public health is
being increasingly recognized. While in recent years a large body evidence has emerged …

Background Cardiovascular disease (CVD) is the leading cause of death worldwide and
considered one of the most environmentally driven diseases. The role of DNA methylation in …

Age-related changes to the genome-wide DNA methylation (DNAm) pattern observed in
blood are well-documented. Clonal hematopoiesis of indeterminate potential (CHIP) …

The complex pathobiology underlying cardiovascular diseases (CVDs) has yet to be
explained. Aberrant epigenetic changes may result from alterations in enzymatic activities …

Background: Epigenetic dysregulation has been proposed as a key mechanism for arsenic-
related cardiovascular disease (CVD). We evaluated differentially methylated positions …

Abstract N6-methyladenosine (m6A) RNA methylation is an emerging area of epigenetics,
which is a reversible and dynamic modification mediating by 'writers'(methylase, adding …

Background Accumulation of deoxyribonucleic acid (DNA) damage diminishes cellular
health, increases the risk of developmental and degenerative diseases and accelerates …

Coronary heart disease (CHD) is a type of cardiovascular disease (CVD) that affects the
coronary arteries, which provide oxygenated blood to the heart. It is a major cause of …

Obesity increases the risk for cardiovascular diseases and induces cardiomyopathy. Chronic
inflammation plays a significant role in obesity-induced cardiomyopathy and may provide …