One of the leading causes of death worldwide these days is cancer, and new anticancer
drugs have been developed to treat it with all the vigor of advancement of science and …

Rethinking placebos: embracing synthetic control arms in clinical trials for rare tumors | Nature
Medicine Skip to main content Thank you for visiting nature.com. You are using a browser …

Data sharing is essential for promoting scientific discoveries and informed decision-making
in clinical practice. In 2013, PhRMA/EFPIA recognised the importance of data sharing and …

Importance The pharmaceutical industry has made substantial investments in developing
processes for sharing individual-participant data (IPD) from clinical trials. However, the utility …

Imagine a theranostic nuclear physician oncologist engaged in a Socratic philosophic
dialogue. Questions that may be posed include the status of our current knowledge base of …

Abstract Objectives Clinical study reports (CSRs) are highly detailed documents that play a
pivotal role in medicine approval processes. Though not historically publicly available, in …

Background Overall survival (OS) results from randomized control trials (RCT) provide the
strongest evidence for efficacy of anti-cancer treatments but can take a considerable amount …

It is not uncommon for industry-sponsored randomized controlled trials to publish survival
curves/data for the overall patient cohort (" A+ B") and for a favorable subgroup (" A") pre …

Pro: Nearly all new devices and drugs come from industry that provides two-thirds of the
funding for medical research, and a much higher fraction of clinical research. Realistically …

Understanding health as a human right creates a legal obligation on countries to ensure
access to timely, acceptable, and affordable health care. We highlight the importance of a …