Covering: 2015 to the end of 2020 Fungal-derived polyketides, non-ribosomal peptides,
terpenoids and their hybrids contribute significantly to the chemical space of total natural …

Oxidative cyclizations are important transformations that occur widely during natural product
biosynthesis. The transformations from acyclic precursors to cyclized products can afford …

Covering: up to September 2015 Meroterpenoids are hybrid natural products that partially
originate from the terpenoid pathway. The meroterpenoids derived from fungi display quite …

Covering: up to July 2019 Terpene synthases (TSs) are responsible for generating much of
the structural diversity found in the superfamily of terpenoid natural products. These elegant …

Meroterpenoids are secondary metabolites formed due to mixed biosynthetic pathways
which are produced in part from a terpenoid co-substrate. These mixed biosynthetically …

A synthetic biology method based on heterologous biosynthesis coupled with genome
mining is a promising approach for increasing the opportunities to rationally access natural …

Anditomin and its precursors, andilesins, are fungal meroterpenoids isolated from
Aspergillus variecolor and have unique, highly oxygenated chemical structures with a …

The discovery of penicillin entailed a decisive breakthrough in medicine. No other medical
advance has ever had the same impact in the clinical practise. The fungus Penicillium …

Penicillium chrysogenum (renamed P. rubens) is the most studied member of a family of
more than 350 Penicillium species that constitute the genus. Since the discovery of penicillin …

Abstract Novofumigatonin (1), isolated from the fungus Aspergillus novofumigatus, is a
heavily oxygenated meroterpenoid containing a unique orthoester moiety. Despite the wide …