Advances in screening, early diagnosis and accurate staging of diabetic neuropathy

J Carmichael, H Fadavi, F Ishibashi… - Frontiers in …, 2021 - frontiersin.org
The incidence of both type 1 and type 2 diabetes is increasing worldwide. Diabetic
peripheral neuropathy (DPN) is among the most distressing and costly of all the chronic …

Mechanistic investigations of diabetic ocular surface diseases

Q Zhou, L Yang, Q Wang, Y Li, C Wei… - Frontiers in …, 2022 - frontiersin.org
With the global prevalence of diabetes mellitus over recent decades, more patients suffered
from various diabetic complications, including diabetic ocular surface diseases that may …

A systematic review on the impact of diabetes mellitus on the ocular surface

K Shih, KSL Lam, L Tong - Nutrition & diabetes, 2017 - nature.com
Diabetes mellitus is associated with extensive morbidity and mortality in any human
community. It is well understood that the burden of diabetes is attributed to chronic …

The impact of diabetes on corneal nerve morphology and ocular surface integrity

M Markoulli, J Flanagan, SS Tummanapalli, J Wu… - The ocular …, 2018 - Elsevier
Diabetes mellitus is a chronic disease that results from inadequate insulin production or
ineffective insulin utilization. It is one of the most common systemic diseases worldwide with …

Diabetic corneal neuropathy

H Mansoor, HC Tan, MTY Lin, JS Mehta… - Journal of clinical …, 2020 - mdpi.com
Diabetic keratopathy (DK) is a common, but underdiagnosed, ocular complication of
diabetes mellitus (DM) that has a significant economic burden. It is characterised by …

Influence of diabetes mellitus on anterior segment of the eye

SB Han, HK Yang, JY Hyon - Clinical interventions in aging, 2019 - Taylor & Francis
Diabetes mellitus (DM) has been emerging as one of the most serious health problems
worldwide. Ocular complications of DM are currently one of the major causes of blindness in …

Small nerve fiber quantification in the diagnosis of diabetic sensorimotor polyneuropathy: comparing corneal confocal microscopy with intraepidermal nerve fiber …

X Chen, J Graham, MA Dabbah, IN Petropoulos… - Diabetes …, 2015 - Am Diabetes Assoc
OBJECTIVE Quantitative assessment of small fiber damage is key to the early diagnosis and
assessment of progression or regression of diabetic sensorimotor polyneuropathy (DSPN) …

Corneal confocal microscopy is a rapid reproducible ophthalmic technique for quantifying corneal nerve abnormalities

A Kalteniece, M Ferdousi, S Adam, J Schofield, S Azmi… - PloS one, 2017 - journals.plos.org
Purpose To assess the effect of applying a protocol for image selection and the number of
images required for adequate quantification of corneal nerve pathology using in vivo corneal …

Diabetic corneal neuropathy as a surrogate marker for diabetic peripheral neuropathy

WZ So, NSQ Wong, HC Tan, MTY Lin… - Neural Regeneration …, 2022 - journals.lww.com
Diabetic neuropathy is a prevalent microvascular complication of diabetes mellitus, affecting
nerves in all parts of the body including corneal nerves and peripheral nervous system …

Corneal confocal microscopy for assessment of diabetic peripheral neuropathy: a meta-analysis

MS Jiang, Y Yuan, ZX Gu, SL Zhuang - British Journal of …, 2016 - bjo.bmj.com
Purpose To evaluate the diagnostic performance of corneal confocal microscopy (CCM) in
assessing corneal nerve parameters in patients with diabetic peripheral neuropathy (DPN) …