Polypharmacy, inappropriate prescribing, and deprescribing in older people: through a sex and gender lens

PA Rochon, M Petrovic, A Cherubini… - The Lancet Healthy …, 2021 - thelancet.com
Polypharmacy is very common in older adults and increases the risk of inappropriate and
unsafe prescribing for older adults. Older adults, particularly women (who make up the …

A systems approach to identifying the challenges of implementing deprescribing in older adults across different health-care settings and countries: a narrative review

M Sawan, E Reeve, J Turner, A Todd… - Expert review of …, 2020 - Taylor & Francis
Introduction: There is increasing recognition of the need for deprescribing of inappropriate
medications in older adults. However, efforts to encourage implementation of deprescribing …

Assessment of attitudes toward deprescribing in older Medicare beneficiaries in the United States

E Reeve, JL Wolff, M Skehan, EA Bayliss… - JAMA internal …, 2018 - jamanetwork.com
Importance Use of harmful and/or unnecessary medications in older adults is prevalent. This
can lead to avoidable harms such as adverse drug reactions, falls, hospitalization, and …

Potentially inappropriate medications in older adults: a population-based cohort study

B Roux, C Sirois, M Simard, ME Gagnon… - Family …, 2020 - academic.oup.com
Background Non-optimal medication use among older adults is a public health concern. A
concrete picture of potentially inappropriate medication (PIM) use is imperative to ensure …

Deprescribing medications for older adults in the primary care context: a mixed studies review

RJ Gillespie, L Harrison, J Mullan - Health science reports, 2018 - Wiley Online Library
Aims This review investigates the factors that influence deprescribing of medications in
primary care from the perspective of general practitioners (GPs) and community‐living older …

The use and misuse of proton pump inhibitors: an opportunity for deprescribing

TS Dharmarajan - Journal of the American Medical Directors Association, 2021 - Elsevier
Proton pump inhibitors (PPIs) are proven medications of choice for gastroesophageal reflux
disease (GERD), acid-related disorders, erosive esophagitis, Barrett esophagus, prevention …

Polypharmacy and deprescribing: challenging the old and embracing the new

LK O'Donnell, K Ibrahim - BMC geriatrics, 2022 - Springer
People are living longer, and the World Health Organisation predicts that by 2050, 22% of
the world's population will be aged 60 years or older [1]. A common consequence of ageing …

Deprescribing as a clinical improvement focus

TS Dharmarajan, H Choi, N Hossain… - Journal of the American …, 2020 - Elsevier
Objectives Polypharmacy is a concern in the practice of geriatrics because of consequences
such as adverse drug events and poorer quality of life. Deprescribing, a response to …

Older patient and caregiver perspectives on medication value and deprescribing: a qualitative study

AN Pickering, ME Hamm, A Dawdani… - Journal of the …, 2020 - Wiley Online Library
OBJECTIVES Shared decision making is essential to deprescribing unnecessary or harmful
medications in older adults, yet patients' and caregivers' perspectives on medication value …

Barriers and enablers of older adults initiating a deprescribing conversation

NJ Ailabouni, KR Weir, E Reeve, JT Turner… - Patient Education and …, 2022 - Elsevier
Objective To examine older adults' perceptions and identify barriers and enablers to
initiating a conversation about stopping medication (s) with their healthcare provider …