CD8+ tumor-infiltrating lymphocytes have been regarded as potential biomarkers for cancer
prognosis, while the prognostic effect of CD8+ tumor-infiltrating T cells remains controversial …

Breast cancer (BC) is the most common malignancy among females. Chemotherapy drugs
remain the cornerstone of treatment of BC and undergo significant shifts over the past 100 …

T cell-based immunotherapies have exhibited promising outcomes in tumor control;
however, their efficacy is limited in immune-excluded tumors. Cancer-associated fibroblasts …

Background This meta-analysis assessed the predictive and prognostic value of tumor
infiltrating lymphocytes (TILs) in neoadjuvant chemotherapy (NACT) treated breast cancer …

The prognostic value of the immune cell infiltrate in the breast carcinoma microenvironment
is still uncertain. We reviewed published articles analysing the infiltration of inflammatory …

Background Tumor microenvironment is infiltrated by many immune cells, of which
Regulatory T (Treg) cells are usually considered as negative regulators of the immune …

Background The value of human leukocyte antigen (HLA; also known as major
histocompatibility complex) class I expression for the prediction of breast cancer survival …

The Oncotype DX 21‑gene test can be used to predict chemotherapy efficacy in patients with
estrogen receptor (ER)‑positive and HER2‑negative breast cancer; however, the data on the …

Loss of HLA-class-I molecule expression by cancer cells is a frequent event in human
tumors that may lead to immune evasion from cytotoxic T-cells. We examined the expression …

Background Breast cancer (BC) is a significant global health issue, accounting for 1 in 8
cancer diagnoses worldwide. HLA class I molecules are typically expressed on the cell …