Noncoding RNA therapeutics—challenges and potential solutions

M Winkle, SM El-Daly, M Fabbri, GA Calin - Nature reviews Drug …, 2021 - nature.com
Therapeutic targeting of noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and
long noncoding RNAs (lncRNAs), represents an attractive approach for the treatment of …

Classical and noncanonical functions of miRNAs in cancers

MP Dragomir, E Knutsen, GA Calin - Trends in Genetics, 2022 - cell.com
Alterations in microRNAs (miRNAs) expression are causative in the initiation and
progression of human cancers. The molecular events responsible for the widespread …

The miRNA: a small but powerful RNA for COVID-19

S Zhang, K Amahong, X Sun, X Lian, J Liu… - Briefings in …, 2021 - academic.oup.com
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is a severe and rapidly evolving epidemic. Now …

Neurobiology of SARS-CoV-2 interactions with the peripheral nervous system: implications for COVID-19 and pain

AJ McFarland, MS Yousuf, S Shiers, TJ Price - Pain reports, 2021 - journals.lww.com
SARS-CoV-2 is a novel coronavirus that infects cells through the angiotensin-converting
enzyme 2 receptor, aided by proteases that prime the spike protein of the virus to enhance …

Neuroinflammation and Its Impact on the Pathogenesis of COVID-19

MM Almutairi, F Sivandzade, TH Albekairi… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). The clinical manifestations of COVID-19 …

miRNAs; a novel strategy for the treatment of COVID‐19

H Ying, M Ebrahimi, M Keivan… - Cell biology …, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is the seventh member of the bat severe
acute respiratory syndrome family. COVID‐19 can fuse their envelopes with the host cell …

MicroRNA mimics or inhibitors as antiviral therapeutic approaches against COVID-19

C Hum, J Loiselle, N Ahmed, TA Shaw, C Toudic… - Drugs, 2021 - Springer
Coronaviruses, such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
responsible for the coronavirus disease 2019 (COVID-19) pandemic, present a significant …

The role of miRNAs in COVID-19 disease

M Fani, M Zandi, S Ebrahimi, S Soltani, S Abbasi - Future Virology, 2021 - Taylor & Francis
Nowadays, the SARS Coronavirus 2 (SARS-CoV-2) infection is recognized as the primary
cause of mortality in humans. SARS-CoV-2 is transmitted through human-to-human contact …

The role of microRNAs in solving COVID-19 puzzle from infection to therapeutics: A mini-review

S Paul, LAB Vázquez, PR Reyes-Pérez… - Virus Research, 2022 - Elsevier
Nowadays, one of the major global health concerns is coronavirus disease 2019 (COVID-
19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

RNA–RNA interactions between SARS-CoV-2 and host benefit viral development and evolution during COVID-19 infection

S Zhang, K Amahong, C Zhang, F Li… - Briefings in …, 2022 - academic.oup.com
Some studies reported that genomic RNA of SARS-CoV-2 can absorb a few host miRNAs
that regulate immune-related genes and then deprive their function. In this perspective, we …