Genome editing (GE) is one of the most efficient and useful molecular approaches to correct
the effects of gene mutations in hereditary monogenetic diseases, including β-thalassemia …

The last few years have seen tremendous advances in CRISPR-mediated genome editing.
Great efforts have been made to improve the efficiency, specificity, editing window, and …

Gene editing by the CRISPR-Cas9 nuclease system technology can be considered among
the most promising strategies to correct hereditary mutations in a variety of monogenic …

CRISPR technologies have overwhelmingly relied on the Streptococcus pyogenes Cas9
(SpyCas9), with its consensus NGG and less preferred NAG and NGA protospacer-adjacent …

Gene editing (GE) is an efficient strategy for correcting genetic mutations in monogenic
hereditary diseases, including β-thalassemia. We have elsewhere reported that CRISPR …

CRISPR-Cas technology, discovered originally as a bacterial defense system, has been
extensively repurposed as a powerful tool for genome editing for multiple applications in …

Extracellular vesicles (EVs) such as microparticles secreted by the cells can be manipulated
and used for delivering therapeutic drugs to target and eradicate cancer cells. However …

Chimeric antigen receptor (CAR)-T and-NK cells showed great success in treating
hematological malignancies, including leukemia, lymphoma, and myeloma. CRISPR …

Recent advances in miniaturized nano-based devices are rapidly extending the boundaries
of biomedical technologies, particularly biosensors. Highly selective biosensors with the …

Salt pans or playas, which are saline-rich springs surrounded by halite evaporates in arid
environments, have played an essential role in landscape erosion during the formation of …