Computational immunogenomic approaches to predict response to cancer immunotherapies
Cancer immunogenomics is an emerging field that bridges genomics and immunology. The
establishment of large-scale genomic collaborative efforts along with the development of …
establishment of large-scale genomic collaborative efforts along with the development of …
Metapipeline-DNA: A comprehensive germline & somatic genomics Nextflow pipeline
DNA sequencing is becoming more affordable and faster through advances in high-
throughput technologies. This rise in data availability has contributed to the development of …
throughput technologies. This rise in data availability has contributed to the development of …
Tumor evolution reconstruction is heavily influenced by algorithmic and experimental choices
R Zaidi, S Zaccaria - Cancer Research, 2024 - aacrjournals.org
Tumor progression is an evolutionary process during which cells acquire distinct genetic
alterations. Several cancer evolutionary studies reconstruct this evolutionary process by …
alterations. Several cancer evolutionary studies reconstruct this evolutionary process by …
A robust benchmark for detecting low-frequency variants in the HG002 Genome In A Bottle NIST reference material.
C Daniels, A Abdulkadir, MH Cleveland, JH McDaniel… - bioRxiv, 2024 - biorxiv.org
Somatic mosaicism is an important cause of disease, but mosaic and somatic variants are
often challenging to detect because they exist in only a fraction of cells. To address the need …
often challenging to detect because they exist in only a fraction of cells. To address the need …