Cellular responses following retinal injuries and therapeutic approaches for neurodegenerative diseases

N Cuenca, L Fernández-Sánchez, L Campello… - Progress in retinal and …, 2014 - Elsevier
Retinal neurodegenerative diseases like age-related macular degeneration, glaucoma,
diabetic retinopathy and retinitis pigmentosa each have a different etiology and …

Cellular stress signaling and the unfolded protein response in retinal degeneration: mechanisms and therapeutic implications

T McLaughlin, A Medina, J Perkins, M Yera… - Molecular …, 2022 - Springer
Background The retina, as part of the central nervous system (CNS) with limited capacity for
self-reparation and regeneration in mammals, is under cumulative environmental stress due …

Aging is not a disease: distinguishing age-related macular degeneration from aging

D Ardeljan, CC Chan - Progress in retinal and eye research, 2013 - Elsevier
Age-related macular degeneration (AMD) is a disease of the outer retina, characterized most
significantly by atrophy of photoreceptors and retinal pigment epithelium accompanied with …

Retinal remodeling

BW Jones, M Kondo, H Terasaki, Y Lin… - Japanese journal of …, 2012 - Springer
Retinal photoreceptor degeneration takes many forms. Mutations in rhodopsin genes or
disorders of the retinal pigment epithelium, defects in the adenosine triphosphate binding …

[HTML][HTML] Extreme retinal remodeling triggered by light damage: implications for age related macular degeneration

RE Marc, BW Jones, CB Watt, F Vazquez-Chona… - Molecular …, 2008 - ncbi.nlm.nih.gov
Purpose Our objective was to comprehensively assess the nature and chronology of neural
remodeling in retinal degenerations triggered by light-induced retinal damage (LIRD) in …

Advances in visual prostheses: engineering and biological challenges

E Borda, D Ghezzi - Progress in Biomedical Engineering, 2022 - iopscience.iop.org
Vision is an extraordinary sense through which we can appreciate the beauty of the world
we live in, gain invaluable knowledge and communicate with others using visual expression …

Retinal remodeling and metabolic alterations in human AMD

BW Jones, RL Pfeiffer, WD Ferrell, CB Watt… - Frontiers in cellular …, 2016 - frontiersin.org
Age-related macular degeneration (AMD) is a progressive retinal degeneration resulting in
central visual field loss, ultimately causing debilitating blindness. AMD affects 18% of …

Ultrastructure of the human retina in aging and various pathological states

TC Nag, S Wadhwa - Micron, 2012 - Elsevier
Vision is hampered in aging and diseases, such as age-related macular degeneration,
retinitis pigmentosa, diabetic retinopathy and glaucoma. This review collates the fine …

Nutritional modulation of age-related macular degeneration

KA Weikel, CJ Chiu, A Taylor - Molecular aspects of medicine, 2012 - Elsevier
Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly
worldwide. It affects 30–50 million individuals and clinical hallmarks of AMD are observed in …

Glaucoma diagnostic ability of layer-by-layer segmented ganglion cell complex by spectral-domain optical coherence tomography

HJ Kim, SY Lee, KH Park, DM Kim… - … & visual science, 2016 - iovs.arvojournals.org
Purpose: To evaluate the diagnostic ability of layer-by-layer segmented macular ganglion
cell complex (GCC) using spectral-domain optical coherence tomography (OCT) for …