Young-onset colorectal cancer
MCW Spaander, AG Zauber, S Syngal… - Nature reviews Disease …, 2023 - nature.com
In the past decades the incidence of colorectal cancer (CRC) in people under the age of 50
years has increased, which is referred to as early-onset CRC or young-onset CRC (YO …
years has increased, which is referred to as early-onset CRC or young-onset CRC (YO …
Genetic predisposition to colorectal cancer: syndromes, genes, classification of genetic variants and implications for precision medicine
This article reviews genes and syndromes associated with predisposition to colorectal
cancer (CRC), with an overview of gene variant classification. We include updates on the …
cancer (CRC), with an overview of gene variant classification. We include updates on the …
[HTML][HTML] Update on genetic predisposition to colorectal cancer and polyposis
The present article summarizes recent developments in the characterization of genetic
predisposition to colorectal cancer (CRC). The main themes covered include new hereditary …
predisposition to colorectal cancer (CRC). The main themes covered include new hereditary …
Gut microbiota and colorectal cancer development: a closer look to the adenoma-carcinoma sequence
M Vacante, R Ciuni, F Basile, A Biondi - Biomedicines, 2020 - mdpi.com
There is wide evidence that CRC could be prevented by regular physical activity, keeping a
healthy body weight, and following a healthy and balanced diet. Many sporadic CRCs …
healthy body weight, and following a healthy and balanced diet. Many sporadic CRCs …
[HTML][HTML] Recent discoveries in the genetics of familial colorectal cancer and polyposis
L Valle - Clinical Gastroenterology and Hepatology, 2017 - Elsevier
The development of genome-wide massively parallel sequencing, ie, whole-genome and
whole-exome sequencing, and copy number approaches has raised high expectations for …
whole-exome sequencing, and copy number approaches has raised high expectations for …
Nanotechnology is an important strategy for combinational innovative chemo-immunotherapies against colorectal cancer
Colorectal cancer (CRC) is among the five most commonly diagnosed cancers worldwide,
constituting 6% of all cancers and the third leading cause of cancer death. CRC is the third …
constituting 6% of all cancers and the third leading cause of cancer death. CRC is the third …
[HTML][HTML] Non-invasive diagnosis of colorectal cancer by Raman spectroscopy: Recent developments in liquid biopsy and endoscopy approaches
H Noothalapati, K Iwasaki, T Yamamoto - Spectrochimica Acta Part A …, 2021 - Elsevier
Colorectal cancer (CRC) is the third most common cancer diagnosed globally and is also
one of the leading causes of cancer deaths in both men and women. The progression of …
one of the leading causes of cancer deaths in both men and women. The progression of …
[HTML][HTML] Genetic evaluation and testing for hereditary forms of cancer in the era of next-generation sequencing
The introduction of next-generation sequencing (NGS) technology in testing for hereditary
cancer susceptibility allows testing of multiple cancer susceptibility genes simultaneously …
cancer susceptibility allows testing of multiple cancer susceptibility genes simultaneously …
Lynch-like syndrome: potential mechanisms and management
A Martínez-Roca, M Giner-Calabuig, O Murcia… - Cancers, 2022 - mdpi.com
Simple Summary Lynch-like syndrome (LLS) is defined as colorectal cancer cases with
microsatellite instability (MSI) and loss of expression of MLH1, MSH2, MSH6, or PMS2 by …
microsatellite instability (MSI) and loss of expression of MLH1, MSH2, MSH6, or PMS2 by …
Impact of a desmoplastic tumor microenvironment for colon cancer drug sensitivity: A study with 3D chimeric tumor spheroids
Three-dimensional (3D) spheroid culture provides opportunities to model tumor growth
closer to its natural context. The collagen network in the extracellular matrix supports …
closer to its natural context. The collagen network in the extracellular matrix supports …