[HTML][HTML] Molecular mechanisms and therapeutic targets for diabetic kidney disease

KR Tuttle, R Agarwal, CE Alpers, GL Bakris… - Kidney international, 2022 - Elsevier
Diabetic kidney disease has a high global disease burden and substantially increases the
risk of kidney failure and cardiovascular events. Despite treatment, there is substantial …

[HTML][HTML] Phenotypic diversity and metabolic specialization of renal endothelial cells

SJ Dumas, E Meta, M Borri, Y Luo, X Li… - Nature Reviews …, 2021 - nature.com
Complex multicellular life in mammals relies on functional cooperation of different organs for
the survival of the whole organism. The kidneys play a critical part in this process through …

[HTML][HTML] What's new in the molecular mechanisms of diabetic kidney disease: recent advances

K Watanabe, E Sato, E Mishima, M Miyazaki… - International journal of …, 2022 - mdpi.com
Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease, including end-
stage kidney disease, and increases the risk of cardiovascular mortality. Although the …

Progenitor-derived endothelin controls dermal sheath contraction for hair follicle regression

P Martino, R Sunkara, N Heitman, M Rangl… - Nature cell …, 2023 - nature.com
Substantial follicle remodelling during the regression phase of the hair growth cycle is
coordinated by the contraction of the dermal sheath smooth muscle, but how dermal-sheath …

Molecular stratification of idiopathic nephrotic syndrome

MA Saleem - Nature Reviews Nephrology, 2019 - nature.com
Idiopathic nephrotic syndrome (INS) describes a group of pathologies of the renal
glomerulus that result in the classic triad of heavy proteinuria, oedema and …

Fibrillin-1–enriched microenvironment drives endothelial injury and vascular rarefaction in chronic kidney disease

L Li, J Liao, Q Yuan, X Hong, J Li, Y Peng, M He… - Science …, 2021 - science.org
Endothelial cell injury leading to microvascular rarefaction is a characteristic feature of
chronic kidney disease (CKD). However, the mechanism underlying endothelial cell dropout …

[HTML][HTML] Renal microcirculation injury as the main cause of ischemic acute kidney injury development

E Kwiatkowska, S Kwiatkowski, V Dziedziejko… - Biology, 2023 - mdpi.com
Simple Summary Acute kidney injury can result from multiple factors. The main cause is
reduced renal perfusion. Kidneys are susceptible to ischemia due to the anatomy of …

The macro-and microcirculation of the kidney

P Guerci, B Ergin, C Ince - Best Practice & Research Clinical …, 2017 - Elsevier
Acute kidney injury (AKI) remains one of the main causes of morbidity and mortality in the
intensive care medicine today. Its pathophysiology and progress to chronic kidney disease …

Studies on the metabolism and mechanism of acteoside in treating chronic glomerulonephritis

W Gao, Y Zhou, C Li, T Liu, H Zhao, M Wang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Acteoside (ACT) is the main ingredient derived from the
leaves of Rehmannia glutinosa (Dihuangye). Dihuangye has the function of clearing heat …

[HTML][HTML] The potential effects of anabolic-androgenic steroids and growth hormone as commonly used sport supplements on the kidney: A systematic review

D Davani-Davari, I Karimzadeh, H Khalili - BMC nephrology, 2019 - Springer
Background Anabolic-androgenic steroids and growth hormone are among the most
commonly used supplements by sportsmen and sportswomen. The aim of this systematic …