Liposomes and liposomes-based drug delivery systems are promising carriers in the rapidly
evolving field of nanomedicine. Liposomes are receiving growing attention in the scientific …

Background Chronic obstructive pulmonary disease (COPD) affects an estimated 14% of
adults in the United States between the ages of 40 and 79 years. This progressive disease is …

Background The chronic and progressive nature of chronic obstructive pulmonary disease
(COPD) requires self-administration of inhaled medication. Dry powder inhalers (DPIs) are …

This work aimed to evaluate the relative inhalation parameters that affect the deposition of
inhaled aerosols, including mouth-throat morphology, airflow rate, and initial condition of …

There is increasing interest in the delivery of drugs to the lungs to treat a variety of diseases.
The spatial and temporal influence of deposition and clearance mechanisms on the fate of …

ABSTRACT Introduction Dry Powder Inhalers (DPIs) continue to be developed to deliver an
expanding range of drugs to treat an ever-increasing range of medical conditions; with each …

Purpose The objective of this study was to explore the performance of a high efficiency dry
powder inhaler (DPI) intended for excipient enhanced growth (EEG) aerosol delivery based …

High-efficiency dry powder inhalers (DPIs) were developed and tested for use with carrier-
free formulations across a range of different inhalation flow rates. Performance of a …

Experimental methods provide means for the quality control of existing DPIs and for
exploring the influence of formulation and device parameters well in advance of clinical trials …

The grid structure is an indispensable part of most dry powder inhalers, but the effects of grid
geometry on inhaler performance are rarely reported. This study aims to systemically …