From Muscle-Based Nonshivering Thermogenesis to Malignant Hyperthermia in Mammals

BS Launikonis, RM Murphy - Annual Review of Physiology, 2025 - annualreviews.org
For physiological processes in the vital organs of eutherian mammals to function, it is
important to maintain constant core body temperature at∼ 37° C. Mammals generate heat …

Functional impact of post-exercise cooling and heating on recovery and training adaptations: Application to resistance, endurance, and sprint exercise

T Chaillou, V Treigyte, S Mosely, M Brazaitis… - Sports medicine …, 2022 - Springer
The application of post-exercise cooling (eg, cold water immersion) and post-exercise
heating has become a popular intervention which is assumed to increase functional …

A machine learning led investigation to understand individual difference and the human-environment interactive effect on classroom thermal comfort

H Lan, HC Hou, Z Gou - Building and Environment, 2023 - Elsevier
The availability of the global thermal open database means that machine learning models
have been increasingly applied in thermal comfort studies in order to understand the factors …

Residual effects of short-term whole-body cold-water immersion on the cytokine profile, white blood cell count, and blood markers of stress

M Eimonte, H Paulauskas… - International Journal …, 2021 - Taylor & Francis
Background: One of the most challenging environmental extremes is immersion in cold/icy
water, and consequent common assumption is that even a brief exposure to cold can lead to …

Remodeling of skeletal muscle myosin metabolic states in hibernating mammals

CTA Lewis, EG Melhedegaard, MM Ognjanovic… - Elife, 2024 - elifesciences.org
Hibernation is a period of metabolic suppression utilized by many small and large mammal
species to survive during winter periods. As the underlying cellular and molecular …

Human body numerical simulation: An accurate model for a thigh subjected to a cold treatment

P Michaux, B Gaume, Y Cong, O Quéméner - Computers in Biology and …, 2024 - Elsevier
This article presents the development of a digital twin model of a thigh portion subjected to
various thermal treatments. Two scenarios are investigated: cold water immersion (CWI) and …

Recovering body temperature from acute cold stress is associated with delayed proinflammatory cytokine production in vivo

M Eimonte, N Eimantas, L Daniuseviciute… - Cytokine, 2021 - Elsevier
A poor outcome of whole-body hypothermia often results from a late complication, rather
than from acute effects of hypothermia. A low body (cell) temperature or the increase in the …

[HTML][HTML] Impairment of adrenergically-regulated thermogenesis in brown fat of obesity-resistant mice is compensated by non-shivering thermogenesis in skeletal …

P Janovska, P Zouhar, K Bardova, J Otahal… - Molecular …, 2023 - Elsevier
Objective Non-shivering thermogenesis (NST) mediated by uncoupling protein 1 (UCP1) in
brown adipose tissue (BAT) can be activated via the adrenergic system in response to cold …

Human vulnerability and variability in the cold: Establishing individual risks for cold weather injuries

F Haman, SCS Souza, JW Castellani, MP Dupuis… - Temperature, 2022 - Taylor & Francis
Human tolerance to cold environments is extremely limited and responses between
individuals is highly variable. Such physiological and morphological predispositions place …

Glacial–Interglacial cycles and early human evolution in China

Z Qin, X Sun - Land, 2023 - mdpi.com
China is a crucial region for investigating the relationship between climate change and
hominin evolution across diverse terrestrial ecosystems. With the continuous development of …