CAR T cell therapies for patients with multiple myeloma

L Mikkilineni, JN Kochenderfer - Nature reviews Clinical oncology, 2021 - nature.com
Despite several therapeutic advances over the past decade, multiple myeloma (MM)
remains largely incurable, indicating a need for new treatment approaches. Chimeric …

Consensus guidelines and recommendations for infection prevention in multiple myeloma: a report from the International Myeloma Working Group

NS Raje, E Anaissie, SK Kumar, S Lonial… - The Lancet …, 2022 - thelancet.com
Infection remains the leading cause of morbidity and mortality in patients with multiple
myeloma because of the cumulative effect of disease, treatment, and host-related factors …

European guidelines for primary antifungal prophylaxis in adult haematology patients: summary of the updated recommendations from the European Conference on …

JA Maertens, C Girmenia… - Journal of …, 2018 - academic.oup.com
Abstract The European Conference on Infections in Leukaemia (ECIL) updated its
guidelines on antifungal prophylaxis for adults using the grading system of IDSA. The …

The expanding field of secondary antibody deficiency: causes, diagnosis, and management

SY Patel, J Carbone, S Jolles - Frontiers in immunology, 2019 - frontiersin.org
Antibody deficiency or hypogammaglobulinemia can have primary or secondary etiologies.
Primary antibody deficiency (PAD) is the result of intrinsic genetic defects, whereas …

CAR-T cell therapy and infection: a review

O Bupha-Intr, G Haeusler, L Chee… - Expert Review of Anti …, 2021 - Taylor & Francis
Introduction: Chimeric antigen receptor T-cell therapy (CAR-T cell therapy) is a novel
immunotherapy with promising results in the treatment of relapsed or refractory B cell …

BCMA-targeting chimeric antigen receptor T-cell therapy for multiple myeloma

J Yang, W Zhou, D Li, T Niu, W Wang - Cancer Letters, 2023 - Elsevier
Multiple myeloma (MM) remains an incurable hematologic malignancy, despite the
development of numerous innovative therapies during the past two decades …

Incidence, timing, and management of infections in patients receiving teclistamab for the treatment of relapsed/refractory multiple myeloma in the MajesTEC‐1 study

AK Nooka, C Rodriguez, MV Mateos, S Manier… - Cancer, 2024 - Wiley Online Library
Background Patients with relapsed/refractory multiple myeloma are at increased risk of
infection. Infections during treatment with teclistamab, the first B‐cell maturation antigen …

Prevention and management of adverse events of novel agents in multiple myeloma: a consensus of the European Myeloma Network

H Ludwig, M Delforge, T Facon, H Einsele, F Gay… - Leukemia, 2017 - nature.com
During the last few years, several new drugs have been introduced for treatment of patients
with multiple myeloma, which have significantly improved treatment outcome. All of these …

Prevention of infections including vaccination strategies in multiple myeloma

H Ludwig, S Kumar - American journal of hematology, 2023 - Wiley Online Library
Infections are a major cause of morbidity and mortality in multiple myeloma. The increased
risk for bacterial and viral infections results mainly from the disease‐inherent and treatment …

Inflammation and infection in plasma cell disorders: how pathogens shape the fate of patients

J Caro, M Braunstein, L Williams, B Bruno… - Leukemia, 2022 - nature.com
The role of infection and chronic inflammation in plasma cell disorders (PCD) has been well-
described. Despite not being a diagnostic criterion, infection is a common complication of …