[HTML][HTML] Recent advances in chemistry and pharmacological aspects of 2-pyridone scaffolds

MMK Amer, MA Aziz, WS Shehab, MH Abdellattif… - Journal of Saudi …, 2021 - Elsevier
Background The chemistry and applications of 2-pyridone structures have recently attracted
a lot of attention due to their uses as synthetic intermediates and their biological importance …

Development of new pyrimidine derivative inhibitor for mild steel corrosion in acid medium

F Benhiba, R Hsissou, K Abderrahim, H Serrar… - Journal of Bio-and Tribo …, 2022 - Springer
The anti-corrosion potency of 8-(4-methoxyphenyl)-3, 6-dioxo-2-(p-tolyl)-3, 6-dihydro-2 H-
thiazolo [3′, 2′: 2, 3][1, 2, 4] triazolo [1, 5-a] pyrimidine-7-carbonitrile (HTPC) was studied …

[HTML][HTML] Magnetic covalent organic framework with ionic tags as an efficient catalyst in the preparation of 2, 3-disubstituted thiazolidine-4-ones and N‑amino-2 …

E Abdoli, M Torabi, M Yarie, MA Zolfigol - Arabian Journal of Chemistry, 2024 - Elsevier
The functionalization of magnetic nanoparticles with covalent organic frameworks (COFs)
will endow them inspiring characteristics. Herein, a new magnetic covalent organic …

Synthesis and Biological Activity of 2-pyridone Derivatives: A Mini Review

KK Verma, S Kapoor, VK Kushwaha… - Letters in Drug …, 2024 - benthamdirect.com
pyridone nucleus is an important scaffold present in various compounds with diverse
pharmacological activity. Among the reported 2-pyridone analogs, the majority of the …

Metalated Azolo[1,2,4]triazines. I. Synthesis of 2‐(6‐tert‐Butyl‐5‐oxo‐4,5‐dihydro‐1,2,4‐triazin‐3(2H)‐ylidene)acetonitriles via Ring Opening Degradation of 3‐tert‐Butyl‐7‐lithio‐4‐oxo‐4 …

SM Ivanov, AM Shestopalov - Journal of Heterocyclic …, 2019 - Wiley Online Library
1, 7, 8‐Polymetalated 3‐tert‐butyl‐8‐R‐4‐oxo‐4H‐pyrazolo [5, 1‐c][1, 2, 4] triazines (M= Li,
Na; R= CO2Et, CN, H, D, and Li) have been generated for the first time using acidic NH …

Synthesis of 2-perfluoroalkyl-1, 4-dihydropyrazolo [1, 5-a][1, 3, 5] triazines via rearrangements of (1-perfluoroacetyl-1, 4-dihydropyrazolo [5, 1-c][1, 2, 4] triazin-4-yl) …

SM Ivanov, JK Voronina, AN Fakhrutdinov… - Journal of Fluorine …, 2019 - Elsevier
tert-Butyl-4-R-1-R1-1, 4-dihydropyrazolo [5, 1-c][1, 2, 4] triazin-4-yl) lithiums (R= SEt, OMe,
OEt; R1= CF3CO, CF2ClCO, CF3CF2CF2CO, t-BuOCO, PhCH2) have been generated for …

7-Aryl-3-(hydroxymethyl)-5-oxo-1,2,3,5-tetrahydro[1,2,4]triazolo[1,5-a]pyridine-6,8-dicarbonitriles: Synthesis and Predicted Biological Activity

AA Dolganov, AG Levchenko, PG Dahno… - Russian Journal of …, 2022 - Springer
Abstract Aminomethylation of 1, 6-diamino-4-aryl-2-oxo-1, 2-dihydropyridine-3, 5-
dicarbonitriles under the action of excess of formaldehyde in ethanol has led to the formation …

Decarboxylation and electrophilic substitution in 3-tert-butyl-4-oxopyrazolo[5,1-c][1,2,4]triazines

SM Ivanov, KA Lyssenko, LM Mironovich… - Russian Chemical …, 2019 - Springer
Abstract Reactivity of 7-R-3-tert-butyl-4-oxo-4, 6-dihydropyrazolo [5, 1-c][1, 2, 4] triazine-8-
carboxylic acids (R= NH 2, N 3, H) and products of their decarboxylation towards different …

1, 6-Diamino-2-oxopyridine-3, 5-dicarbonitrile derivatives in the Mannich reaction

VV Dotsenko, AN Khrustaleva, KA Frolov… - Russian Journal of …, 2021 - Springer
Diamino-2-oxo-1, 2, 3, 4-tetrahydropyridine-3, 5-dicarbonitriles under the action of primary
aliphatic amines and an excess of 37% formalin in ethanol were converted into 2, 3, 8, 9 …

Synthesis of N-substituted sulfonamides containing perhalopyridine moiety as bio-active candidates

R Hosseini, R Ranjbar-Karimi… - Journal of Fluorine …, 2020 - Elsevier
A series of new halogenated aryl sulfonamides, as bio-active candidates, was synthesized
from the reaction of the corresponding aryl sulfonamides with pentafluoro-and …