Terpenoid transport in plants: how far from the final picture?

OC Demurtas, A Nicolia, G Diretto - Plants, 2023 - mdpi.com
Contrary to the biosynthetic pathways of many terpenoids, which are well characterized and
elucidated, their transport inside subcellular compartments and the secretion of reaction …

Utilizing plant synthetic biology to improve human health and wellness

CR Barnum, BJ Endelman, PM Shih - Frontiers in Plant Science, 2021 - frontiersin.org
Plants offer a vast source of bioactive chemicals with the potential to improve human health
through the prevention and treatment of disease. However, many potential therapeutics are …

EASI Transformation: An Efficient Transient Expression Method for Analyzing Gene Function in Catharanthus roseus Seedlings

S Mortensen, D Bernal-Franco, LF Cole… - Frontiers in plant …, 2019 - frontiersin.org
The Catharanthus roseus plant is the exclusive source of the valuable anticancer terpenoid
indole alkaloids, vinblastine (VB) and vincristine (VC). The recent availability of …

Identification of Iridoid Glucoside Transporters in Catharanthus roseus

B Larsen, VL Fuller, J Pollier… - Plant and Cell …, 2017 - academic.oup.com
Monoterpenoid indole alkaloids (MIAs) are plant defense compounds and high-value
pharmaceuticals. Biosynthesis of the universal MIA precursor, secologanin, is organized …

Developmental Methylome of the Medicinal Plant Catharanthus roseus Unravels the Tissue-Specific Control of the Monoterpene Indole Alkaloid Pathway by DNA …

T Dugé de Bernonville, S Maury, A Delaunay… - International Journal of …, 2020 - mdpi.com
Catharanthus roseus produces a wide spectrum of monoterpene indole alkaloids (MIAs).
MIA biosynthesis requires a tightly coordinated pathway involving more than 30 enzymatic …

Diurnal metabolic regulation of isoflavones and soyasaponins in soybean roots

H Matsuda, M Nakayasu, Y Aoki, S Yamazaki… - Plant …, 2020 - Wiley Online Library
Isoflavones and soyasaponins are major specialized metabolites accumulated in soybean
roots and secreted into the rhizosphere. Unlike the biosynthetic pathway, the transporters …

Silencing of oleuropein β-glucosidase abolishes the biosynthetic capacity of secoiridoids in olives

K Koudounas, M Thomopoulou, A Rigakou… - Frontiers in Plant …, 2021 - frontiersin.org
Specialized metabolism is an evolutionary answer that fortifies plants against a wide
spectrum of (a) biotic challenges. A plethora of diversified compounds can be found in the …

Post-Cyclization Skeletal Rearrangements in Plant Triterpenoid Biosynthesis by a Pair of Branchpoint Isomerases

L Chuang, S Liu, J Franke - Journal of the American Chemical …, 2023 - ACS Publications
Triterpenoids possess potent biological activities, but their polycyclic skeletons are
challenging to synthesize. The skeletal diversity of triterpenoids in plants is generated by …

An optimized screen reduces the number of GA transporters and provides insights into nitrate transporter 1/peptide transporter family substrate determinants

N Wulff, HA Ernst, ME Jørgensen, S Lambertz… - Frontiers in Plant …, 2019 - frontiersin.org
Based on recent in vitro data, a relatively large number of the plant nitrate transporter
1/peptide transporter family (NPF) proteins have been suggested to function as gibberellic …

Establishment of virus-induced gene silencing system and functional analysis of ScbHLH17 in Senecio cruentus

Y Li, Y Liu, F Qi, C Deng, C Lu, H Huang… - Plant Physiology and …, 2020 - Elsevier
Virus-induced gene silencing (VIGS) is a technology for rapid gene functional analysis that
depends on the degradation of viral RNA and is part of the natural defense mechanism in …