Intestinal microbiota, fecal microbiota transplantation, and inflammatory bowel disease

AR Weingarden, BP Vaughn - Gut microbes, 2017 - Taylor & Francis
Inflammatory bowel disease (IBD) is a complex set of diseases that lead to chronic
inflammation in the gastrointestinal tract. Although the etiology of IBD is not fully understood …

Revisiting inflammatory bowel disease: pathology, treatments, challenges and emerging therapeutics including drug leads from natural products

K Yeshi, R Ruscher, L Hunter, NL Daly… - Journal of clinical …, 2020 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic and life-long disease characterized by
gastrointestinal tract inflammation. It is caused by the interplay of the host's genetic …

Helminth infections and host immune regulation

HJ McSorley, RM Maizels - Clinical microbiology reviews, 2012 - Am Soc Microbiol
Helminth parasites infect almost one-third of the world's population, primarily in tropical
regions. However, regions where helminth parasites are endemic record much lower …

Helminth immunomodulation in autoimmune disease

TB Smallwood, PR Giacomin, A Loukas… - Frontiers in …, 2017 - frontiersin.org
Helminths have evolved to become experts at subverting immune surveillance. Through
potent and persistent immune tempering, helminths can remain undetected in human …

Cross-domain and viral interactions in the microbiome

AD Rowan-Nash, BJ Korry, E Mylonakis… - … and Molecular Biology …, 2019 - Am Soc Microbiol
The importance of the microbiome to human health is increasingly recognized and has
become a major focus of recent research. However, much of the work has focused on a few …

Helminth parasites–masters of regulation

RM Maizels, A Balic, N Gomez‐Escobar… - Immunological …, 2004 - Wiley Online Library
Immune regulation by parasites is a global concept that includes suppression, diversion,
and conversion of the host immune response to the benefit of the pathogen. While many …

Trichuris suis therapy in Crohn's disease

RW Summers, DE Elliott, JF Urban, R Thompson… - Gut, 2005 - gut.bmj.com
Background: Crohn's disease is common in highly industrialised Western countries where
helminths are rare and uncommon in less developed areas of the world where most people …

Serotonin has a key role in pathogenesis of experimental colitis

JE Ghia, N Li, H Wang, M Collins, Y Deng… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: Mucosal changes in inflammatory bowel disease are characterized
by ulcerative lesions accompanied by a prominent infiltrate of immune cells as well as …

Infectious diseases, autoantibodies, and autoimmunity

D Johnson, W Jiang - Journal of autoimmunity, 2023 - Elsevier
Infections are known to trigger flares of autoimmune diseases in humans and serve as an
inciting cause of autoimmunity in animals. Evidence suggests a causative role of infections …

Chronic helminth infections induce immunomodulation: consequences and mechanisms

E van Riet, FC Hartgers, M Yazdanbakhsh - Immunobiology, 2007 - Elsevier
Worldwide, more than a billion people are infected with helminths. These worm infections
generally do not lead to mortality, however, they are chronic in nature and can lead to …