Adult neurogenesis and functional plasticity in neuronal circuits

PM Lledo, M Alonso, MS Grubb - Nature Reviews Neuroscience, 2006 - nature.com
The adult brain is a plastic place. To ensure that the mature nervous system's control of
behaviour is flexible in the face of a varying environment, morphological and physiological …

Adult neurogenesis: from precursors to network and physiology

DN Abrous, M Koehl, M Le Moal - Physiological reviews, 2005 - journals.physiology.org
The discovery that the adult mammalian brain creates new neurons from pools of stemlike
cells was a breakthrough in neuroscience. Interestingly, this particular new form of structural …

Abnormalities in hippocampal functioning with persistent pain

AA Mutso, D Radzicki, MN Baliki, L Huang… - Journal of …, 2012 - Soc Neuroscience
Chronic pain patients exhibit increased anxiety, depression, and deficits in learning and
memory. Yet how persistent pain affects the key brain area regulating these behaviors, the …

Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusion in adult rats

H Scharfman, J Goodman, A Macleod, S Phani… - Experimental …, 2005 - Elsevier
There is evidence that BDNF influences the birth of granule cells in the dentate gyrus, which
is one of the few areas of the brain that demonstrates neurogenesis throughout life …

Stimulation of entorhinal cortex promotes adult neurogenesis and facilitates spatial memory

SSD Stone, CM Teixeira, LM DeVito… - Journal of …, 2011 - Soc Neuroscience
Deep brain stimulation (DBS) is an established therapeutic modality for the treatment of
movement disorders and an emerging therapeutic approach for the treatment of disorders of …

Environmental enrichment and voluntary exercise massively increase neurogenesis in the adult hippocampus via dissociable pathways

AK Olson, BD Eadie, C Ernst, BR Christie - Hippocampus, 2006 - Wiley Online Library
Environmental enrichment (EE) and voluntary exercise (VEx) have consistently been shown
to increase adult hippocampal neurogenesis and improve spatial learning ability. Although it …

GABA sets the tempo for activity-dependent adult neurogenesis

S Ge, DA Pradhan, G Ming, H Song - Trends in neurosciences, 2007 - cell.com
GABA, a major inhibitory neurotransmitter in the adult brain, activates synaptic and
extrasynaptic GABA A receptors, causing hyperpolarization of mature neurons. As in the …

Adult neurogenesis and repair of the adult CNS with neural progenitors, precursors, and stem cells

JG Emsley, BD Mitchell, G Kempermann… - Progress in …, 2005 - Elsevier
Recent work in neuroscience has shown that the adult central nervous system contains
neural progenitors, precursors, and stem cells that are capable of generating new neurons …

The neurogenesis hypothesis of affective and anxiety disorders: are we mistaking the scaffolding for the building?

D Petrik, DC Lagace, AJ Eisch - Neuropharmacology, 2012 - Elsevier
Hypotheses are scaffoldings erected in front of a building and then dismantled when the
building is finished. They are indispensable for the workman; but you mustn't mistake the …

Decreased adult hippocampal neurogenesis in the PDAPP mouse model of Alzheimer's disease

MH Donovan, U Yazdani, RD Norris… - Journal of …, 2006 - Wiley Online Library
Abnormal subgranular zone (SGZ) neurogenesis is proposed to contribute to Alzheimer's
disease (AD)‐related decreases in hippocampal function. Our goal was to examine …