DN Abrous, M Koehl, M Le Moal - Physiological reviews, 2005 - journals.physiology.org
The discovery that the adult mammalian brain creates new neurons from pools of stemlike cells was a breakthrough in neuroscience. Interestingly, this particular new form of structural …
AA Mutso, D Radzicki, MN Baliki, L Huang… - Journal of …, 2012 - Soc Neuroscience
Chronic pain patients exhibit increased anxiety, depression, and deficits in learning and memory. Yet how persistent pain affects the key brain area regulating these behaviors, the …
There is evidence that BDNF influences the birth of granule cells in the dentate gyrus, which is one of the few areas of the brain that demonstrates neurogenesis throughout life …
Deep brain stimulation (DBS) is an established therapeutic modality for the treatment of movement disorders and an emerging therapeutic approach for the treatment of disorders of …
AK Olson, BD Eadie, C Ernst, BR Christie - Hippocampus, 2006 - Wiley Online Library
Environmental enrichment (EE) and voluntary exercise (VEx) have consistently been shown to increase adult hippocampal neurogenesis and improve spatial learning ability. Although it …
GABA, a major inhibitory neurotransmitter in the adult brain, activates synaptic and extrasynaptic GABA A receptors, causing hyperpolarization of mature neurons. As in the …
JG Emsley, BD Mitchell, G Kempermann… - Progress in …, 2005 - Elsevier
Recent work in neuroscience has shown that the adult central nervous system contains neural progenitors, precursors, and stem cells that are capable of generating new neurons …
Hypotheses are scaffoldings erected in front of a building and then dismantled when the building is finished. They are indispensable for the workman; but you mustn't mistake the …
MH Donovan, U Yazdani, RD Norris… - Journal of …, 2006 - Wiley Online Library
Abnormal subgranular zone (SGZ) neurogenesis is proposed to contribute to Alzheimer's disease (AD)‐related decreases in hippocampal function. Our goal was to examine …