Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) are uniquely
required to balance the formation of new blood vessels with the maintenance and …

The monolayer of endothelial cells lining the vessel wall forms a semipermeable barrier (in
all tissue except the relatively impermeable blood–brain and inner retinal barriers) that …

Angiogenesis is a multistep process that requires coordinated migration, proliferation, and
junction formation of vascular endothelial cells (ECs) to form new vessel branches in …

Endothelial cells line blood vessels and provide a dynamic interface between the blood and
tissues. They remodel to allow leukocytes, fluid and small molecules to enter tissues during …

The pulmonary endothelium is a dynamic, metabolically active layer of squamous
endothelial cells ideally placed to mediate key processes involved in lung homoeostasis …

Angiogenesis and vascular remodeling are essential for the establishment of vascular
networks during organogenesis. Here we show that the Hippo signaling pathway effectors …

The actin cytoskeleton plays a crucial role in many cellular processes while its
reorganization is important in maintaining cell homeostasis. However, in the case of cancer …

Tissue injury to skin diminishes miR-200b in dermal fibroblasts. Fibroblasts are widely
reported to directly reprogram into endothelial-like cells and we hypothesized that miR-200b …

Morphogenesis of hierarchical vascular networks depends on the integration of multiple
biomechanical signals by endothelial cells, the cells lining the interior of blood vessels …

Endothelial cells lining blood vessels regulate vascular barrier function, which controls the
passage of plasma proteins and circulating cells across the endothelium. In most normal …