Large-conductance Ca2+-and voltage-activated K+ (BK) channels play many physiological
roles ranging from the maintenance of smooth muscle tone to hearing and neurosecretion …

Potassium channels are particularly important in determining the shape and duration of the
action potential, controlling the membrane potential, modulating hormone secretion …

KCNMA1 encodes the pore-forming α subunit of the “Big K+”(BK) large conductance calcium
and voltage-activated K+ channel. BK channels are widely distributed across tissues …

Potassium (K+) ion channel activity is an important determinant of vascular tone by
regulating cell membrane potential (MP). Activation of K+ channels leads to membrane …

Calcium and voltage-activated potassium (BK) channels are key actors in cell physiology,
both in neuronal and non-neuronal cells and tissues. Through negative feedback between …

The mechanisms through which aldosterone promotes apparently opposite effects like salt
reabsorption and K+ secretion remain poorly understood. The identification, localization …

The large-conductance calcium-and voltage-activated K+ channel (BKCa) are encoded by
the Kcnma1 gene. They are ubiquitously expressed in neuronal, smooth muscle, astrocytes …

2 Hypertension June 2018 observed in individuals with the maximum sodium excretion
combined with the lowest potassium excretion. 8 Similarly, a cluster-randomized controlled …

Modulation of Na+-Cl− cotransporter (NCC) activity is essential to adjust K+ excretion in the
face of changes in dietary K+ intake. We used previously characterized genetic mouse …

The central goal of this overview article is to summarize recent findings in renal epithelial
transport, focusing chiefly on the connecting tubule (CNT) and the cortical collecting duct …