Biological features of extracellular vesicles and challenges

Y Zeng, Y Qiu, W Jiang, J Shen, X Yao, X He… - Frontiers in Cell and …, 2022 - frontiersin.org
Extracellular vesicles (EVs) are vesicles with a lipid bilayer membrane on the outside, which
are widely found in various body fluids and contain biological macromolecules such as …

Circulating exosomal mRNA signatures for the early diagnosis of clear cell renal cell carcinoma

X He, F Tian, F Guo, F Zhang, H Zhang, J Ji, L Zhao… - BMC medicine, 2022 - Springer
Background There are no proven tumor biomarkers for the early diagnosis of clear cell renal
cell carcinoma (ccRCC) thus far. This study aimed to identify novel biomarkers of ccRCC …

Kidney Cancer and Potential Use of Urinary Extracellular Vesicles

LNH Le, J Munir, EB Kim, S Ryu - Oncology Reviews, 2024 - frontiersin.org
Kidney cancer is the 14th most common cancer globally. The 5-year relative survival rate of
kidney cancer at a localized stage is 92.9% and it declines to 17.4% in metastatic stage …

Extracellular vesicles related gene HSPH1 exerts anti-tumor effects in prostate cancer via promoting the stress response of CD8+ T cells

X Wu, Y Zhu, C Hu, X Du, W Xue, Y Chen, L Dong… - Cellular Oncology, 2024 - Springer
Background T cell stress response state (TSTR), as a novel immune concept previous
studies have proposed, has not yet been explored in prostate cancer (PC). As a type of …

Identification of novel snoRNA-based biomarkers for clear cell renal cell carcinoma from urine-derived extracellular vesicles

K Grützmann, K Salomo, A Krüger, A Lohse-Fischer… - Biology Direct, 2024 - Springer
Background Clear cell renal cell carcinoma (ccRCC) is the most common subtype of RCC
with high rates of metastasis. Targeted therapies such as tyrosine kinase and checkpoint …

Extracellular vesicles and inflammatory diseases

P Mitra, I Kumar, S Gupta - Extracellular Vesicles in Human Health and …, 2024 - Springer
Extracellular vesicles (EVs) are intercellular communication mediators that play crucial roles
in a variety of physiological and pathological processes. Their role in inflammatory diseases …

Systems approaches to cell culture-derived extracellular vesicles for acute kidney injury therapy: Prospects and challenges

DJ Lundy, B Szomolay, CT Liao - Function, 2024 - academic.oup.com
Acute kidney injury (AKI) is a heterogeneous syndrome, comprising diverse etiologies of
kidney insults that result in high mortality and morbidity if not well managed. Although great …

[HTML][HTML] Extracellular Vesicles in Kidney Disease

C Lv - 2023 - intechopen.com
The kidney is the mainly apparatus in the human body, with a complex organizational
structure and diverse pathological changes closely related to other organs. Extracellular …

Extracellular Vesicles—A new potential player in the Immunology of Renal Cell Carcinoma

M Kleibert, M Majka, K Łakomska… - Journal of Personalized …, 2022 - mdpi.com
The incidence of renal cell carcinoma (RCC) has doubled in the developed world within the
last fifty years, and now it is responsible for 2–3% of diagnosed cancers. The delay in …

[PDF][PDF] The Role of Urinary Extracellular Vesicles in Kidney Cancer: Diagnostic and Therapeutic Potential

K Gallego - auo.asmepress.com
Renal cancer ranks as the 14th most common cancer globally, with renal cell carcinoma
(RCC) being the primary variant, arising from renal tubular epithelial cells; clear cell RCC …