Innate immunity represents the semi-specific first line of defense and provides the initial host
response to tissue injury, trauma, and pathogens. Innate immunity activates the adaptive …

Primary Sjögren syndrome (pSS) is a progressive autoimmune disease characterized by
sicca and systemic manifestations. In this Review, we summarize the available data on …

Objective Alterations in the microbiota composition of the gastro-intestinal tract are
suspected to be involved in the etiopathogenesis of two closely related systemic …

A complex balanced equilibrium of the bacterial ecosystems exists in the oral cavity that can
be altered by tobacco smoking, psychological stressors, bad dietary habit, and chronic …

The human microbiome consists of all microorganisms occupying the skin, mucous
membranes and intestinal tract of the human body. The contact of the mucosal immune …

Oral microbiota dysbiosis is associated with the occurrence and progression of oral cancer.
To investigate the association between the microbiota and risk of oral squamous cell …

Pulmonary involvement in primary Sjögren's syndrome (pSS) is an understudied entity with
important clinical implications. Its prevalence has been reported in up to 20% of pSS …

Key events in the pathogenesis of Sjӧgren syndrome (SS) include the change of salivary
gland epithelial cells into antigen-presenting cell-like phenotypes and focal lymphocytic …

Background Reduced salivation is considered a major clinical feature of most but not all
cases of primary Sjögren's syndrome (pSS). Reduced saliva flow may lead to changes in the …

Background The relationship between periodontal diseases and Sjogren's syndrome were
found inconsistent in current studies. Our objective is to clarify the relationship between …