Hypoxia is caused by a cancer-promoting milieu characterized by persistent inflammation.
NF-κB and HIF-1α are critical participants in this transition. Tumor development and …

Metabolic syndrome (MetS), which is characterized by insulin resistance, high blood
glucose, obesity, and dyslipidemia, is known to increase the risk of dementia accompanied …

Simple Summary Understanding the role of the plasma membrane in the responses of
cancer cells to chemotherapy is important because the cell membrane is directly involved in …

It is well known that solid hypoxic tumour cells oxidise glucose through glycolysis, and the
end product of this pathway is fermented into lactate which accumulates in the tumour …

Colorectal cancer (CRC) is the third most common cancer and the second most deadly
cancer worldwide. Nevertheless, more than 70% of CRC cases are resulted from sporadic …

Cognitive decline, the primary clinical phenotype of Alzheimer's disease (AD), is currently
attributed mainly to amyloid and tau protein deposits. However, a growing body of evidence …

Dysfunction of the ubiquitin‒proteasome system can induce sustained endoplasmic
reticulum stress (ERS) and subsequent cell death. However, malignant cells have evolved …

This Perspective is dedicated to the 25th Anniversary of Biomacromolecules. It provides a
personal view on the developing field of the polymer and biology interface over the 25 years …

Ultraviolet B (UVB) radiation induces oxidative stress in skin cells, generating reactive
oxygen species (ROS) and perturbing enzyme-mediated metabolism. This disruption is …

Intrauterine growth restriction (IUGR) predisposes to chronic kidney disease via activation of
proinflammatory pathways, and omega-3 PUFAs (n-3 PUFAs) have anti-inflammatory …