Metabolic reprogramming is a hallmark of cancer development, progression, and
metastasis. Several metabolic pathways such as glycolysis, tricarboxylic acid (TCA) cycle …

Type 2 diabetes mellitus is a complex metabolic disease that is caused by insulin resistance
and β-cell dysfunction. Furthermore, type 2 diabetes has an evident genetic component and …

GLUT4 is the primary glucose transporter in adipose and skeletal muscle tissues. Its cellular
trafficking is regulated by insulin signaling. Failed or reduced plasma membrane localization …

Abstract Study Objectives: The sleep-deprivation-induced changes in delta power, an
electroencephalographical correlate of sleep need, and brain transcriptome profiles have …

The outlined recent findings advanced our understanding of the molecular regulation of
SGK1 as well as the role of the kinase in renal physiology and the pathophysiology of renal …

The mechanistic target of rapamycin, mTOR, controls cell metabolism in response to growth
signals and stress stimuli. The cellular functions of mTOR are mediated by two distinct …

Acute stress causes rapid release of norepinephrine (NE) and glucocorticoids (GCs), both of
which bind to hippocampal receptors. This release continues, at varying concentrations, for …

Compelling evidence is accumulating indicating a pathophysiological role of the serum-and-
glucocorticoid-inducible-kinase-1 (SGK1) in the development and complications of diabetes …

Osteoporosis (OP) is a common age-related systemic skeletal disease, with a strong genetic
component, characterised by loss of bone mass and strength, which leads to increased …

The serum and glucocorticoid inducible kinase SGK1 is genomically upregulated by
glucocorticoids and in turn stimulates a variety of carriers and channels including the renal …