ABSTRACT Cajal-Retzius neurons (CRs) are among the first-born neurons in the
developing cortex of reptiles, birds and mammals, including humans. The peculiarity of CRs …

Tangential migration is a mode of cell movement, which in the developing cerebral cortex, is
defined by displacement parallel to the ventricular surface and orthogonal to the radial glial …

Early B cell factor 3 (EBF3) is a member of the highly evolutionarily conserved
Collier/Olf/EBF (COE) family of transcription factors. Prior studies on invertebrate and …

Zinc-finger E-box binding homeobox 1 (Zeb1) is a key regulator of epithelial-mesenchymal
transition and cancer metastasis. Mutation of ZEB1 is associated with human diseases and …

The specification of neuronal subtypes in the cerebral cortex proceeds in a temporal
manner; however, the regulation of the transitions between the sequentially generated …

Early B cell factor 3 (EBF3) is an atypical transcription factor that is thought to influence the
laminar formation of the cerebral cortex. Here, we report that de novo mutations in EBF3 …

Infantile spasms are a catastrophic form of pediatric epilepsy with inadequate treatment. In
patients, mutation of ARX, a transcription factor selectively expressed in neuronal precursors …

Craniofacial disorders arise in early pregnancy and are one of the most common congenital
defects. To fully understand how craniofacial disorders arise, it is essential to characterize …

In the neocortex, higher-order areas are essential to integrate sensory-motor information
and have expanded in size during evolution. How higher-order areas are specified …

Background V0v spinal interneurons are highly conserved, glutamatergic, commissural
neurons that function in locomotor circuits. We have previously shown that Evx1 and Evx2 …