Macrophage Trafficking, Inflammatory Resolution, and Genomics in Atherosclerosis: JACC Macrophage in CVD Series (Part 2)

KJ Moore, S Koplev, EA Fisher, I Tabas… - Journal of the American …, 2018 - jacc.org
Atherosclerosis is characterized by the retention of modified lipoproteins in the arterial wall.
These modified lipoproteins activate resident macrophages and the recruitment of monocyte …

Monocyte differentiation and heterogeneity: inter-subset and interindividual differences

H Williams, C Mack, R Baraz, R Marimuthu… - International Journal of …, 2023 - mdpi.com
The three subsets of human monocytes, classical, intermediate, and nonclassical, show
phenotypic heterogeneity, particularly in their expression of CD14 and CD16. This has …

Macrophages in vascular inflammation and atherosclerosis

C Cochain, A Zernecke - Pflügers Archiv-European Journal of Physiology, 2017 - Springer
Atherosclerosis is characterized by lipid accumulation and chronic inflammation of the
arterial wall, and its main complications—myocardial infarction and ischemic stroke …

Junctional adhesion molecules (JAMs): cell adhesion receptors with pleiotropic functions in cell physiology and development

K Ebnet - Physiological reviews, 2017 - journals.physiology.org
Junctional adhesion molecules (JAM)-A,-B and-C are cell-cell adhesion molecules of the
immunoglobulin superfamily which are expressed by a variety of tissues, both during …

Angiogenic factor-driven inflammation promotes extravasation of human proangiogenic monocytes to tumours

A Sidibe, P Ropraz, S Jemelin, Y Emre… - Nature …, 2018 - nature.com
Recruitment of circulating monocytes is critical for tumour angiogenesis. However, how
human monocyte subpopulations extravasate to tumours is unclear. Here we show …

Atherosclerosis: integration of its pathogenesis as a self-perpetuating propagating inflammation: a review

RN Poston - Cardiovascular endocrinology & metabolism, 2019 - journals.lww.com
This review proposes that the development of the atherosclerotic plaque is critically
dependent on its inflammatory components forming a self-perpetuating and propagating …

The roles of junctional adhesion molecules (JAMs) in cell migration

J Wang, H Liu - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
The review briefly summarizes the role of the family of adhesion molecules, JAMs (junctional
adhesion molecules), in various cell migration, covering germ cells, epithelial cells …

The diverse roles of macrophages in metabolic inflammation and its resolution

A Guha Ray, OP Odum, D Wiseman… - Frontiers in Cell and …, 2023 - frontiersin.org
Macrophages are one of the most functionally diverse immune cells, indispensable to
maintain tissue integrity and metabolic health. Macrophages perform a myriad of functions …

Junctional adhesion molecules: Potential proteins in atherosclerosis

J Wang, X Chen - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Junctional adhesion molecules (JAMs) are cell-cell adhesion molecules of the
immunoglobulin superfamily and are involved in the regulation of diverse atherosclerosis …

Epigenetic regulation in monocyte/macrophage: a key player during atherosclerosis

SJ Jia, KQ Gao, M Zhao - Cardiovascular therapeutics, 2017 - Wiley Online Library
Atherosclerosis is a chronic inflammatory disease. Recently, a growing body of evidence
emphasizes that the monocyte and macrophage differentiation and activation are key …