MYC: a multipurpose oncogene with prognostic and therapeutic implications in blood malignancies
MYC oncogene is a transcription factor with a wide array of functions affecting cellular
activities such as cell cycle, apoptosis, DNA damage response, and hematopoiesis. Due to …
activities such as cell cycle, apoptosis, DNA damage response, and hematopoiesis. Due to …
HIV-associated cancers and related diseases
R Yarchoan, TS Uldrick - New England Journal of Medicine, 2018 - Mass Medical Soc
AIDS-Associated Cancers Cancer is a leading cause of death in patients with AIDS. The
incidence of AIDS-defining cancers has been stable owing to highly active antiretroviral …
incidence of AIDS-defining cancers has been stable owing to highly active antiretroviral …
The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications
E Campo, SH Swerdlow, NL Harris… - Blood, The Journal …, 2011 - ashpublications.org
Abstract The World Health Organization classification of lymphoid neoplasms updated in
2008 represents a worldwide consensus on the diagnosis of these tumors and is based on …
2008 represents a worldwide consensus on the diagnosis of these tumors and is based on …
The biology and treatment of plasmablastic lymphoma
Plasmablastic lymphoma (PBL) is an aggressive lymphoma commonly associated with HIV
infection. However, PBL can also be seen in patients with other immunodeficiencies as well …
infection. However, PBL can also be seen in patients with other immunodeficiencies as well …
HIV-associated cancers and lymphoproliferative disorders caused by Kaposi sarcoma herpesvirus and Epstein-Barr virus
KA Lurain, R Ramaswami, LT Krug… - Clinical Microbiology …, 2024 - journals.asm.org
Within weeks of the first report of acquired immunodeficiency syndrome (AIDS) in 1981, it
was observed that these patients often had Kaposi sarcoma (KS), a hitherto rarely seen skin …
was observed that these patients often had Kaposi sarcoma (KS), a hitherto rarely seen skin …
Double-hit B-cell lymphomas
SM Aukema, R Siebert, ED Schuuring… - Blood, The Journal …, 2011 - ashpublications.org
In many B-cell lymphomas, chromosomal translocations are biologic and diagnostic
hallmarks of disease. An intriguing subset is formed by the so-called double-hit (DH) …
hallmarks of disease. An intriguing subset is formed by the so-called double-hit (DH) …
Diffuse large B-cell lymphoma variants: an update
Diffuse large B-cell lymphoma (DLBCL) is the most common type of lymphoma, representing
approximately one-third of all cases worldwide. In the World Health Organization (WHO) …
approximately one-third of all cases worldwide. In the World Health Organization (WHO) …
Understanding MYC-driven aggressive B-cell lymphomas: pathogenesis and classification
G Ott, A Rosenwald, E Campo - Blood, The Journal of the …, 2013 - ashpublications.org
MYC is a potent oncogene initially identified as the target of the t (8; 14)(q24; q32)
chromosome translocation in Burkitt lymphoma. MYC gene alterations have been identified …
chromosome translocation in Burkitt lymphoma. MYC gene alterations have been identified …
The role of c-MYC in B-cell lymphomas: diagnostic and molecular aspects
L Nguyen, P Papenhausen, H Shao - Genes, 2017 - mdpi.com
c-MYC is one of the most essential transcriptional factors, regulating a diverse array of
cellular functions, including proliferation, growth, and apoptosis. Dysregulation of c-MYC is …
cellular functions, including proliferation, growth, and apoptosis. Dysregulation of c-MYC is …
Clinicopathologic comparison of plasmablastic lymphoma in HIV-positive, immunocompetent, and posttransplant patients: single-center series of 25 cases and meta …
J Morscio, D Dierickx, J Nijs, G Verhoef… - The American Journal …, 2014 - journals.lww.com
Plasmablastic lymphoma (PBL) is a rare B-cell non-Hodgkin lymphoma often associated
with Epstein-Barr virus (EBV) infection. To gain insight in this aggressive lymphoma subtype …
with Epstein-Barr virus (EBV) infection. To gain insight in this aggressive lymphoma subtype …