Almost all transcribed human genes undergo alternative RNA splicing, which increases the
diversity of the coding and non-coding cellular landscape. The resultant gene products …

The advent of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) has revolutionized
the treatment of acute promyelocytic leukemia (APL), resulting in excellent rates of remission …

The introduction of all-trans retinoic acid combined with anthracyclines has significantly
improved the outcomes for patients diagnosed with acute promyelocytic leukemia (APL) …

Arsenic trioxide (ATO) and all‐trans retinoic acid (ATRA) form the backbone of the treatment
of acute promyelocytic leukaemia (APL), with the addition of chemotherapy for high‐risk …

The introduction of all-trans retinoic acid combined with anthracyclines has significantly
improved the outcomes for patients diagnosed with acute promyelocytic leukemia (APL) …

Acute promyelocytic leukemia (APL) is associated with a favorable long-term prognosis if
appropriate treatment is initiated promptly. Outcomes in clinical trials and population-based …

Association between comorbidity burden and patient outcomes has not been adequately
investigated in acute promyelocytic leukemia (APL). We utilized the National Cancer …

Previous studies have shown that socioeconomic factors play an important role in multiple
myeloma (MM) health outcomes. We postulated that the type of treatment facilities and their …

Background Early death remains a major factor in survival in APL. We aimed to analyze the
risk factors for differentiation syndrome and early death in acute promyelocytic leukemia …

Acute promyelocytic leukemia (APL) is a highly curable hematologic malignancy in the era
of all-trans retinoic acid (ATRA) combination treatment. However, only a modest change in …