Towards a dynamic interaction network of life to unify and expand the evolutionary theory

E Bapteste, P Huneman - BMC biology, 2018 - Springer
The classic Darwinian theory and the Synthetic evolutionary theory and their linear models,
while invaluable to study the origins and evolution of species, are not primarily designed to …

Differentially expressed genes and molecular susceptibility to human age-related diseases

S Shikhevich, I Chadaeva, B Khandaev… - International Journal of …, 2023 - mdpi.com
Mainstream transcriptome profiling of susceptibility versus resistance to age-related
diseases (ARDs) is focused on differentially expressed genes (DEGs) specific to gender …

Feifukang ameliorates pulmonary fibrosis by inhibiting JAK-STAT signaling pathway

H Li, Z Wang, J Zhang, Y Wang, C Yu, J Zhang… - … and alternative medicine, 2018 - Springer
Background Feifukang (FFK) is a traditional Chinese medicine composed of herbs that
protect lung function. However, difficulty arises regarding the clinical application of FFK due …

Phylostratigraphic Analysis Shows the Earliest Origination of the Abiotic Stress Associated Genes in A. thaliana

ZS Mustafin, VI Zamyatin, DK Konstantinov… - Genes, 2019 - mdpi.com
Plants constantly fight with stressful factors as high or low temperature, drought, soil salinity
and flooding. Plants have evolved a set of stress response mechanisms, which involve …

Candidate SNP markers significantly altering the affinity of TATA-binding protein for the promoters of human hub genes for atherogenesis, atherosclerosis and …

A Bogomolov, S Filonov, I Chadaeva… - International Journal of …, 2023 - mdpi.com
Atherosclerosis is a systemic disease in which focal lesions in arteries promote the build-up
of lipoproteins and cholesterol they are transporting. The development of atheroma …

DERL3 functions as a tumor suppressor in gastric cancer

Y Li, H Liu, H Chen, J Shao, F Su, S Zhang… - … Biology and Chemistry, 2020 - Elsevier
Background Gastric cancer is a common malignant tumor in the clinic with a high mortality
rate, ranking the first among malignant tumors of the digestive system. Early gastric cancer …

[HTML][HTML] Improving readability of static, straight-line graph drawings: A first look at edge crossing resolution through iterative vertex splitting

H Ehlers, A Villedieu, RG Raidou, HY Wu - Computers & Graphics, 2023 - Elsevier
We present a novel vertex-splitting approach to iteratively resolve edge crossings in order to
improve the readability of graph drawings. Dense graphs, even when small in size (10 to 15 …

Nine Genes Mediate the Therapeutic Effects of Iodine‐131 Radiotherapy in Thyroid Carcinoma Patients

H Shuwen, Y Xi, D Miao, X Jiamin, Z Jing… - Disease …, 2020 - Wiley Online Library
Background. Thyroid carcinoma (THCA) is one of the most common malignancies of the
endocrine system, which is usually treated by surgery combined with iodine‐131 (I131) …

Bioinformatic Analysis Reveals the Role of Translation Elongation Efficiency Optimisation in the Evolution of Ralstonia Genus

AY Korenskaia, YG Matushkin, ZS Mustafin, SA Lashin… - Biology, 2023 - mdpi.com
Simple Summary Bacteria belonging to the Ralstonia genus are of great interest for study
since this genus includes both phytopathogenic species and soil opportunistic human …

[HTML][HTML] A novel tailored immune gene pairs signature for overall survival prediction in lower-grade gliomas

X Pan, Z Wang, F Liu, F Zou, Q Xie, Y Guo… - Translational Oncology, 2021 - Elsevier
Lower-grade gliomas (LGGs) have a good prognosis with a wide range of overall survival
(OS) outcomes. An accurate prognostic system can better predict survival time. An RNA …