The oral microbiome: Role of key organisms and complex networks in oral health and disease

L Sedghi, V DiMassa, A Harrington… - Periodontology …, 2021 - Wiley Online Library
States of oral health and disease reflect the compositional and functional capacities of, as
well as the interspecies interactions within, the oral microbiota. The oral cavity exists as a …

The noncanonical pathway for in vivo nitric oxide generation: the nitrate-nitrite-nitric oxide pathway

V Kapil, RS Khambata, DA Jones, K Rathod… - Pharmacological …, 2020 - Elsevier
In contrast to nitric oxide, which has well established and important roles in the regulation of
blood flow and thrombosis, neurotransmission, the normal functioning of the genitourinary …

Effects of Chlorhexidine mouthwash on the oral microbiome

R Bescos, A Ashworth, C Cutler, ZL Brookes… - Scientific reports, 2020 - nature.com
Following a single blind, cross-over and non-randomized design we investigated the effect
of 7-day use of chlorhexidine (CHX) mouthwash on the salivary microbiome as well as …

[HTML][HTML] Spatial ecology of the human tongue dorsum microbiome

SA Wilbert, JLM Welch, GG Borisy - Cell reports, 2020 - cell.com
A fundamental question in microbial ecology is how microbes are spatially organized with
respect to each other and their host. A test bed for examining this question is the tongue …

Dietary nitrate and nitric oxide metabolism mouth, circulation, skeletal muscle, and exercise performance

AM Jones, A Vanhatalo, DR Seals, MJ Rossman… - 2020 - nih.brage.unit.no
Nitric oxide (NO) is a gaseous signaling molecule that plays an important role in myriad
physiological processes including the regulation of vascular tone, neurotransmission …

[HTML][HTML] Mouthwash effects on the oral microbiome: are they good, bad, or balanced?

Z Brookes, L Teoh, F Cieplik, P Kumar - international dental journal, 2023 - Elsevier
This narrative review describes the oral microbiome, and its role in oral health and disease,
before considering the impact of commonly used over-the-counter (OTC) mouthwashes on …

How periodontal disease and presence of nitric oxide reducing oral bacteria can affect blood pressure

P Pignatelli, G Fabietti, A Ricci, A Piattelli… - International journal of …, 2020 - mdpi.com
Nitric oxide (NO), a small gaseous and multifunctional signaling molecule, is involved in the
maintenance of metabolic and cardiovascular homeostasis. It is endogenously produced in …

Illuminating the oral microbiome and its host interactions: animal models of disease

G Hajishengallis - FEMS Microbiology Reviews, 2023 - academic.oup.com
Periodontitis and caries are driven by complex interactions between the oral microbiome
and host factors, ie inflammation and dietary sugars, respectively. Animal models have been …

Chlorhexidine digluconate mouthwash alters the oral microbial composition and affects the prevalence of antimicrobial resistance genes

S Bartsch, E Kohnert, C Kreutz, JP Woelber… - Frontiers in …, 2024 - frontiersin.org
Introduction Chlorhexidine (CHX) is a commonly used antiseptic in situations of limited oral
hygiene ability such as after periodontal surgery. However, CHX is also considered as a …

Periodontitis, blood pressure, and the risk and control of arterial hypertension: epidemiological, clinical, and pathophysiological aspects—review of the literature and …

S Surma, M Romańczyk, J Witalińska-Łabuzek… - Current Hypertension …, 2021 - Springer
Abstract Purpose of Review Arterial hypertension is an important risk factor for
cardiovascular disease. In the world, about 45% of people suffer from arterial hypertension …