Viewing metabolism through the lens of exercise biology has proven an accessible and
practical strategy to gain new insights into local and systemic metabolic regulation. Recent …

Together, loss-and gain-of-function experiments have identified the bone-derived secreted
molecule osteocalcin as a hormone with a broad reach in rodents and primates. Following …

Extensive research has found strongly increased generation of reactive oxygen species, free
radicals, and reactive nitrogen species during acute physical exercise that can lead to …

Aberrant amino acid metabolism is a common event in obesity. Particularly, subjects with
obesity are characterized by the excessive plasma kynurenine (Kyn). However, the primary …

Physical exercise has gradually become a focus in cancer treatment due to its pronounced
role in reducing cancer risk, enhancing therapeutic efficacy, and improving prognosis. In …

Interleukin-6 is a pleiotropic cytokine regulating different tissues and organs in diverse and
sometimes discrepant ways. The dual and sometime hermetic nature of IL-6 action has been …

Abstract Interleukin (IL)-6 elicits both anticancer and procancer effects depending on the
context, which we have termed the 'exercise IL-6 enigma'. IL-6 is released from skeletal …

Label-free electrochemical immunosensors (ELFIs) are becoming increasingly
indispensable tools in life science, medicine, chemistry, and biotechnology. They combine …

Exercise confers numerous salutary effects that extend beyond individual organ systems to
provide systemic health benefits. Here, we discuss the role of exercise in cardiovascular …

The cytokine interleukin‐6 (IL‐6) is involved in a diverse set of physiological processes.
Traditionally, IL‐6 has been thought of in terms of its inflammatory actions during the acute …