Phenol-soluble modulins and staphylococcal infection

A Peschel, M Otto - Nature Reviews Microbiology, 2013 - nature.com
Staphylococcus aureus is an important human pathogen and a leading cause of death
worldwide. Phenol-soluble modulins (PSMs) have recently emerged as a novel toxin family …

Phenol-soluble modulins–critical determinants of staphylococcal virulence

GYC Cheung, HS Joo, SS Chatterjee… - FEMS microbiology …, 2014 - academic.oup.com
Phenol-soluble modulins (PSMs) are a recently discovered family of amphipathic, alpha-
helical peptides that have multiple roles in staphylococcal pathogenesis and contribute to a …

Direct antimicrobial resistance prediction from clinical MALDI-TOF mass spectra using machine learning

C Weis, A Cuénod, B Rieck, O Dubuis, S Graf… - Nature Medicine, 2022 - nature.com
Early use of effective antimicrobial treatments is critical for the outcome of infections and the
prevention of treatment resistance. Antimicrobial resistance testing enables the selection of …

Staphylococcus aureus Hemolysins, bi-component Leukocidins, and Cytolytic Peptides: A Redundant Arsenal of Membrane-Damaging Virulence Factors?

F Vandenesch, G Lina, T Henry - Frontiers in cellular and infection …, 2012 - frontiersin.org
One key aspect of the virulence of Staphylococcus aureus lies in its ability to target the host
cell membrane with a large number of membrane-damaging toxins and peptides. In this …

MRSA virulence and spread

M Otto - Cellular microbiology, 2012 - Wiley Online Library
Methicillin‐resistant S taphylococcus aureus (MRSA) is one of the most frequent causes of
hospital‐and community‐associated infections. Resistance to the entire class of β‐lactam …

Detection of antibiotic-resistance by MALDI-TOF mass spectrometry: an expanding area

W Florio, L Baldeschi, C Rizzato, A Tavanti… - Frontiers in cellular …, 2020 - frontiersin.org
Several MALDI-TOF MS-based methods have been proposed for rapid detection of
antimicrobial resistance. The most widely studied methods include assessment of β …

Staphylococcus aureus toxins–their functions and genetics

D Grumann, U Nübel, BM Bröker - Infection, Genetics and Evolution, 2014 - Elsevier
The outcome of encounters between Staphylococcus (S.) aureus and its human host ranges
from life-threatening infection through allergic reactions to symptom-free colonization. The …

Coagulase‐negative staphylococci as reservoirs of genes facilitating MRSA infection: Staphylococcal commensal species such as Staphylococcus epidermidis are …

M Otto - Bioessays, 2013 - Wiley Online Library
Recent research has suggested that Staphylococcus epidermidis is a reservoir of genes
that, after horizontal transfer, facilitate the potential of Staphylococcus aureus to colonize …

[PDF][PDF] Genomic Basis for Methicillin Resistance in Staphylococcus aureus

K Hiramatsu, T Ito, S Tsubakishita… - Infection & …, 2013 - synapse.koreamed.org
Since the discovery of the first strain in 1961 in England, MRSA, the most notorious
multidrug-resistant hospital pathogen, has spread all over the world. MRSA repeatedly …

Current concepts on the virulence mechanisms of meticillin-resistant Staphylococcus aureus

RR Watkins, MZ David… - Journal of medical …, 2012 - microbiologyresearch.org
Meticillin-resistant Staphylococcus aureus (MRSA) strains are prevalent bacterial pathogens
that cause both health care and community-associated infections. Increasing resistance to …