How I personalize fluid therapy in septic shock?

X Monnet, C Lai, JL Teboul - Critical Care, 2023 - Springer
During septic shock, fluid therapy is aimed at increasing cardiac output and improving tissue
oxygenation, but it poses two problems: it has inconsistent and transient efficacy, and it has …

Identifying and characterizing high-risk clusters in a heterogeneous ICU population with deep embedded clustering

J Castela Forte, G Yeshmagambetova… - Scientific reports, 2021 - nature.com
Critically ill patients constitute a highly heterogeneous population, with seemingly distinct
patients having similar outcomes, and patients with the same admission diagnosis having …

Data augmentation for electrocardiograms

A Raghu, D Shanmugam… - … on Health, Inference …, 2022 - proceedings.mlr.press
Neural network models have demonstrated impressive performance in predicting
pathologies and outcomes from the 12-lead electrocardiogram (ECG). However, these …

Are classic bedside exam findings required to initiate enteral nutrition in critically ill patients: emphasis on bowel sounds and abdominal distension

AM Deane, Y Ali Abdelhamid… - Nutrition in Clinical …, 2021 - Wiley Online Library
The general physical examination of a patient is an axiom of critical care medicine, but
evidence to support this practice remains sparse. Given the lack of evidence for a …

Deep embedded clustering generalisability and adaptation for integrating mixed datatypes: two critical care cohorts

JWTM de Kok, F van Rosmalen, J Koeze, F Keus… - Scientific Reports, 2024 - nature.com
Abstract We validated a Deep Embedded Clustering (DEC) model and its adaptation for
integrating mixed datatypes (in this study, numerical and categorical variables). Deep …

Burden of acute kidney injury and 90-day mortality in critically ill patients

R Wiersema, RJ Eck, M Haapio, J Koeze… - BMC nephrology, 2020 - Springer
Background Mortality rates associated with acute kidney injury (AKI) vary among critically ill
patients. Outcomes are often not corrected for severity or duration of AKI. Our objective was …

[HTML][HTML] Non-invasive oscillometric versus invasive arterial blood pressure measurements in critically ill patients: A post hoc analysis of a prospective observational …

T Kaufmann, EGM Cox, R Wiersema, B Hiemstra… - Journal of critical …, 2020 - Elsevier
Purpose The aim was to compare non-invasive blood pressure measurements with invasive
blood pressure measurements in critically ill patients. Methods Non-invasive blood pressure …

Cardiac output, heart rate and stroke volume during targeted temperature management after out-of-hospital cardiac arrest: association with mortality and cause of …

J Grand, J Kjaergaard, J Bro-Jeppesen, M Wanscher… - Resuscitation, 2019 - Elsevier
Aim Myocardial dysfunction and low cardiac index are common after out-of-hospital cardiac
arrest (OHCA) as part of the post-cardiac arrest syndrome. This study investigates the …

Capillary refill time for the management of acute circulatory failure: a survey among pediatric and adult intensivists

M Jacquet-Lagrèze, C Wiart, R Schweizer… - BMC emergency …, 2022 - Springer
Introduction Recent studies have shown the prognostic value of capillary refill time (CRT)
and suggested that resuscitation management guided by CRT may reduce morbidity and …

External validation of mortality prediction models for critical illness reveals preserved discrimination but poor calibration

EGM Cox, R Wiersema, RJ Eck, T Kaufmann… - Critical Care …, 2023 - journals.lww.com
OBJECTIVES: In a recent scoping review, we identified 43 mortality prediction models for
critically ill patients. We aimed to assess the performances of these models through external …