Background Widely used for acute pain management, the clinical benefit from perioperative
use of gabapentinoids is uncertain. The aim of this systematic review was to assess the …

This article reviews and summarizes current evidence and knowledge gaps regarding
postoperative analgesia after pediatric posterior spine fusion for adolescent idiopathic …

Although pain is regarded as a global public health priority, analgesic therapy remains a
significant challenge. Pain is a hypersensitivity state caused by peripheral and central …

The treatment of acute pain requires special attention when focused on older adults, who
are usually defined as those age 65 years or older. Various physiologic changes occur with …

Background Development of a widely accepted standardised analgesic pathway for adult
spine surgery has been hampered by the lack of quantitative analysis. We conducted a …

Gabapentin is a structural analogue of the inhibitory neurotransmitter gammaaminobutyric
acid (GABA); however, it has little activity at the GABA receptors. Instead, it is thought that …

Anesthesia for posterior spinal fusion for adolescent idiopathic scoliosis remains one of the
most common surgeries performed in adolescents. These procedures have the potential for …

Utilization of opioids for acute pain control during surgical procedures is commonplace for
anesthesia providers. Opioid use is associated with many undesirable side effects, including …

Abstract Background and Objectives Gabapentin and pregabalin have been considered
relatively safe opioid-sparing adjuncts for pain management. However, rising prescribing …

Gabapentinoid drugs (pregabalin and gabapentin) have been successfully used in the
treatment of neuropathic pain and in focal seizure prevention. Recent research has …