Inflammasomes are supramolecular platforms that organize in response to various damage-
associated molecular patterns and pathogen-associated molecular patterns. Upon …

The expression of cytokines and chemokines in response to adenovirus infection is tightly
regulated by the innate immune system. Cytokine-mediated toxicity and cytokine storm are …

Adenovirus pneumonia is common in pediatric upper respiratory tract infection, which is
comparatively easy to develop into severe cases and has a high mortality rate with many …

It is well-known that viruses activate various inflammasomes, which can initiate the
programmed cell death pathway known as pyroptosis, subsequently leading to cell lysis and …

The interplay between pathogen and host determines the immune response during viral
infection. The Nod‑like receptor (NLR) protein 3 inflammasome is a multiprotein complex …

Inflammasome-mediated caspase-1 activation facilitates innate immune control of
Plasmodium in the liver, thereby limiting the incidence and severity of clinical malaria …

Viral diseases are the most common problems threatening human health, livestock, and
poultry industries worldwide. Viral infection is a complex and competitive dynamic biological …

Simple Summary Inflammasomes are multiprotein complexes that sense endogenous
damage stimuli and diverse microbial pathogens, including viruses. A growing body of …

Background As an organelle essential for intracellular energy supply, mitochondria are
involved in intracellular metabolism and inflammation, and cell death. The interaction of …

Sepsis is defined as a life-threatening organ dysfunction induced by a dysregulated host
immune response to infection. Immune response induced by sepsis is complex and …