Silent battles: immune responses in asymptomatic SARS-CoV-2 infection

N Le Bert, T Samandari - Cellular & Molecular Immunology, 2024 - nature.com
SARS-CoV-2 infections manifest with a broad spectrum of presentations, ranging from
asymptomatic infections to severe pneumonia and fatal outcomes. This review centers on …

Organokines in COVID-19: a systematic review

SM Barbalho, G Minniti, VFB Miola, JFS Haber… - Cells, 2023 - mdpi.com
Coronavirus disease 2019 (COVID-19) is a viral infection caused by SARS-CoV-2 that
induces a generalized inflammatory state. Organokines (adipokines, osteokines, myokines …

Identification of genes associated with the impairment of olfactory and gustatory functions in COVID-19 via machine-learning methods

J Ren, Y Zhang, W Guo, K Feng, Y Yuan, T Huang… - Life, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19), as a severe respiratory disease, affects many
parts of the body, and approximately 20–85% of patients exhibit functional impairment of the …

Bovine lactoferrin inhibits SARS‐CoV‐2 and SARS‐CoV‐1 by targeting the RdRp complex and alleviates viral infection in the hamster model

S He, H Qin, L Guan, K Liu, B Hong… - Journal of Medical …, 2023 - Wiley Online Library
Breast milk has been found to inhibit coronavirus infection, while the key components and
mechanisms are unknown. We aimed to determine the components that contribute to the …

[HTML][HTML] Pre-infection antiviral innate immunity contributes to sex differences in SARS-CoV-2 infection

N Sauerwald, Z Zhang, I Ramos, VD Nair… - Cell Systems, 2022 - cell.com
Male sex is a major risk factor for SARS-CoV-2 infection severity. To understand the basis for
this sex difference, we studied SARS-CoV-2 infection in a young adult cohort of United …

High plasma levels of fibroblast growth factor 23 are associated with increased risk of COVID-19 in end-stage renal disease patients on hemodialysis: results of a …

L Toro, L Michea, A Parra-Lucares, G Mendez-Valdes… - Toxins, 2023 - mdpi.com
End-stage renal disease (ESRD) patients are a population with high rates of COVID-19 and
mortality. These patients present a low response to anti-SARS-CoV-2 immunization, which is …

Cross-protective HCoV immunity reduces symptom development during SARS-CoV-2 infection

IA Abela, M Schwarzmüller, A Ulyte, T Radtke… - Mbio, 2024 - Am Soc Microbiol
Numerous clinical parameters link to severe coronavirus disease 2019, but factors that
prevent symptomatic disease remain unknown. We investigated the impact of severe acute …

A genome-wide association study for survival from a multi-centre European study identified variants associated with COVID-19 risk of death

F Minnai, F Biscarini, M Esposito, TA Dragani… - Scientific Reports, 2024 - nature.com
The clinical manifestations of SARS-CoV-2 infection vary widely among patients, from
asymptomatic to life-threatening. Host genetics is one of the factors that contributes to this …

Proinflammatory cytokine profiles in both mild symptomatic and asymptomatic SARS-CoV-2-infected Egyptian individuals and a proposed relationship to post-COVID …

MM Bahgat, R Nadeem, MH Nasraa, K Amer… - Viral …, 2023 - liebertpub.com
Severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection is associated
with proinflammatory cytokine release as mediators of host antiviral response to the …

FGF7 enhances the expression of ACE2 in human islet organoids aggravating SARS-CoV-2 infection

H Meng, Z Liao, Y Ji, D Wang, Y Han… - … and Targeted Therapy, 2024 - nature.com
The angiotensin-converting enzyme 2 (ACE2) is a primary cell surface viral binding receptor
for SARS-CoV-2, so finding new regulatory molecules to modulate ACE2 expression levels …