A review of recent developments of metal–organic frameworks as combined biomedical platforms over the past decade

M Moharramnejad, RE Malekshah, A Ehsani… - Advances in Colloid and …, 2023 - Elsevier
Abstract Metal–organic frameworks (MOFs), also called porous coordination polymers,
represent a class of crystalline porous materials made up of organic ligands and metal …

Recent developments on the potential biological applications of transition metal complexes of thiosemicarbazone derivatives

V Singh, VNV Palakkeezhillam, V Manakkadan… - Polyhedron, 2023 - Elsevier
This review talks about the synthesis, and coordination chemistry of thiosemicarbazone and
its bonding with transition metals like copper, nickel, zinc, palladium, and ruthenium and …

Fabrication, characterization, and application of wound dressing based on PVP/PVA nanofibers containing β-cyclodextrin/curcumin complex: From in silico to in vitro …

H Derakhshankhah, RE Malekshah, Z Izadi… - Journal of Molecular …, 2023 - Elsevier
The β-cyclodextrin-curcumin (β-CD-Cur) complex was applied in this study to modify the
PVP nanofibers. The complexation of the Cur with β-CD was investigated using density …

Influence of Indole-N Substitution of Thiosemicarbazones in Cationic Ru(II)(η6-Benzene) Complexes on Their Anticancer Activity

N Balakrishnan, J Haribabu, M Dharmasivam… - …, 2023 - ACS Publications
Indole thiosemicarbazones (TSCs) and their complexes are known to possess various
biological activities. The variation in anticancer activity with different indole-N substituents of …

Synthesis and characterization of N4-substituted thiosemicarbazones: DNA/BSA binding, molecular docking, anticancer activity, ADME study and computational …

V Manakkadan, J Haribabu… - Journal of Molecular …, 2023 - Elsevier
A series of thiosemicarbazones with the general formula, R− CHdouble bondN− NH− C (S)−
R 1 [R= C 6 H 5 F & R 1= C 4 H 9 NO (TL1), R= C 8 H 10 O 2 & R 1= C 4 H 9 NO (TL2), R= C …

Synthesis, DFT investigation, ADME-T properties, molecular docking and molecular dynamics simulation of new α-aminophosphonate inhibitor targeting Mpro and …

R Kerkour, O Moumeni, N El houda Rabhi… - Journal of Molecular …, 2024 - Elsevier
A specific α-aminophosphonate molecule, namely diethyl (phenyl (4-pyridinylamino) methyl)
phosphonate (α-DAP), as a potential SARS-CoV-2 inhibitor, has been synthesized via a …

Synthesis, crystal structure, Hirshfeld surface analysis, DFT, molecular docking and in vitro antitumor studies of (2E)-2-[4-(diethylamino) benzylidene]-N …

K Preetha, EB Seena, PK Maniyampara… - Journal of Molecular …, 2024 - Elsevier
The crystal structure and spectral characterization of a new proligand,(2E)-2-[4-
(diethylamino) benzylidene]-N-ethylhydrazinecarbothioamide is described. The compound …

N-Indolyl diiron vinyliminium complexes exhibit antiproliferative effects in cancer cells associated with disruption of mitochondrial homeostasis, ROS scavenging, and …

G Bresciani, J Cervinka, H Kostrhunova… - Chemico-Biological …, 2023 - Elsevier
The indole scaffold has been established as a key organic moiety for developing new drugs;
on the other hand, a range of diiron bis-cyclopentadienyl complexes have recently emerged …

Novel Mn (II) and Cu (II) metal complexes with sulfa drug-derived ligands as potent antimicrobial and anticancer agents: In vitro studies, ADMET profile and molecular …

MA Bourouai, A Bouchoucha, KS Larbi, S Cosnier… - Polyhedron, 2024 - Elsevier
The present work deals with the synthesis, characterization, and pharmaceutical potential
evaluation of new biologically active Mn (II) and Cu (II) complexes with Schiff bases derived …

New aromatic hydrazones: Synthesis, structural analysis, DFT study, biological activity, ADME-T properties and in silico evaluation of their inhibition of SAS-CoV-2 …

L Adjissi, N Chafai, K Benbouguerra, I Kirouani… - Journal of Molecular …, 2023 - Elsevier
Three new hydrazones namely:(2E)-1-(4-methylphenyl-2-[(thiophen-2-yl) methylidene]
hydrazine (HZ-1),(2E)-1-(4-methylphenyl)-2-[(thiophen-3yl) methylidene] hydrazine (HZ-2) …