Chemokine dysregulation and neuroinflammation in schizophrenia: a systematic review

EA Ermakov, IA Mednova, AS Boiko… - International Journal of …, 2023 - mdpi.com
Chemokines are known to be immunoregulatory proteins involved not only in lymphocyte
chemotaxis to the site of inflammation, but also in neuromodulation, neurogenesis, and …

Regulation of CNS precursor function by neuronal chemokines

AES Watson, K Goodkey, T Footz, A Voronova - Neuroscience letters, 2020 - Elsevier
Oligodendrocyte and neural precursor cells (OPCs and NPCs, respectively) in the central
nervous system (CNS) have diverse roles in development and homeostasis. During …

Monocyte count in schizophrenia and related disorders: a systematic review and meta-analysis

MG Mazza, M Capellazzi, S Lucchi, I Tagliabue… - Acta …, 2020 - cambridge.org
Objective: Increasing evidence suggests that immunological and inflammatory dysfunctions
may play an important role in predisposition, onset, and progression of schizophrenia and …

The association of cognitive performance and IL-6 levels in schizophrenia is influenced by age and antipsychotic treatment

R Ribeiro-Santos, SM de Campos-Carli… - Nordic journal of …, 2020 - Taylor & Francis
Aims: Recent findings suggest that cognitive impairment can be associated with
inflammation and immune changes in schizophrenia. We aimed to study possible …

[HTML][HTML] Effects of Chitosan and N-Succinyl Chitosan on Metabolic Disorders Caused by Oral Administration of Olanzapine in Mice

B Shagdarova, V Melnikova, V Kostenko… - Biomedicines, 2024 - mdpi.com
Background: The issue of human mental health is gaining more and more attention
nowadays. However, most mental disorders are treated with antipsychotic drugs that cause …

Effect of chemokine gene variants on Covid-19 disease severity

S Dogan, SZ Mart Komurcu, MD Korkmaz… - Immunological …, 2022 - Taylor & Francis
Patients immune phenotype/genotype data may be useful to understand the molecular
mechanisms involved in SARS-CoV-2 infection and can contribute to the identify the …

[HTML][HTML] Target discovery using deep learning-based molecular docking and predicted protein structures with alphafold for novel antipsychotics

Y Kim, S Kim - Psychiatry Investigation, 2023 - ncbi.nlm.nih.gov
Objective New drugs are needed to treat antipsychotic-resistant schizophrenia, especially
those with clozapine-resistant schizophrenia. Atypical antipsychotics have predominantly 5 …

Impact of SARS-CoV-2 on host factors involved in mental disorders

R Rhoades, S Solomon, C Johnson… - Frontiers in Microbiology, 2022 - frontiersin.org
COVID-19, caused by SARS-CoV-2, is a systemic illness due to its multiorgan effects in
patients. The disease has a detrimental impact on respiratory and cardiovascular systems …

[HTML][HTML] Immunophenotyping schizophrenia subtypes stratified by antipsychotic response

Y Li, JWX Ong, YM See, JY Yee, C Tang… - Brain, Behavior, and …, 2025 - Elsevier
Immune dysfunction has been proposed to play a role in the pathophysiology behind the
development and persistence of psychosis. Current immunophenotyping studies are limited …

Involvement of CXCL10 rs4256246, CXCR4 rs2228014, CCR2 rs1799864 and CXCL16 rs2277680 in the Predisposition to Schizophrenia

H Saoud, H Foddha, Y Aflouk, BBH Jrad - Journal of Molecular …, 2024 - Springer
Chemokine ligands and their receptors have acquired less attention than pro-and anti-
inflammatory cytokines in schizophrenia (SCZ). Thus, we aimed to examine the impact of …