Glucagon like-peptide 1 (GLP-1) within the brain is produced by a population of
preproglucagon neurons located in the caudal nucleus of the solitary tract. These neurons …

Abstract Glucagon-like peptide-1 (GLP-1) is a multifunctional polypeptide throughout the
lifespan via activating Glucagon-like peptide-1 receptor (GLP-1R). GLP-1 can affect food …

In this study, we aimed to investigate the associations between Sirt6, macrophages and
diabetic nephropathy (DN). Immunohistochemical, western blot and RT‑qPCR analyses …

This study investigated the neuroprotective effects of exendin-4 (EXE-4), an analog of the
glucagon-like peptide 1 receptor (GLP-1R) on memory and on the neuronal populations that …

Introduction Schizophrenia is a neuropsychiatric disorder that affects approximately 1% of
individuals worldwide. There are no available medications to treat cognitive impairment in …

Background and aims Advanced glycation end products (AGEs) and receptor of advanced
glycation end products (RAGE), are associated with cognition decline. We aim to investigate …

Objective: Previous studies have provided robust evidence that cognitive impairment exists
in patients with type 2 diabetes. The predictive role of S100B in a variety of …

Diabetes mellitus (DM) is a chronic disease characterized by elevated blood glucose levels
caused by a lack of insulin production (type 1 diabetes) or insulin resistance (type 2 …

Using male Zucker diabetic fatty (ZDF) rats implanted subcutaneously with polyethylene
mesh pieces stimulating granulation tissue development, we investigated the effects of the in …

Astrocytes are crucial for the maintenance of brain homeostasis by actively participating in
the metabolism of glucose, which is the main energy substrate for the central nervous …