Essential proteins are vital for an organism's viability under a variety of conditions. There are
many experimental and computational methods developed to identify essential proteins …

Infectious diseases caused by pathogens, including viruses, bacteria and parasites, pose a
serious threat to human health worldwide. Frequent changes in the pattern of infection …

While genome sequencing projects have generated tremendous amounts of protein
sequence data for a vast number of genomes, substantial portions of most genomes are still …

The analysis of protein-protein interactions is fundamental to the understanding of cellular
organization, processes, and functions. Recent large-scale investigations of protein-protein …

Essential proteins are indispensable to cellular life. Identification of essential proteins plays
a critical role in the survival and development of life process and understanding the function …

Interactome analyses have traditionally been applied to yeast, human and other model
organisms due to the availability of protein–protein interaction data for these species …

Using a series of immunoprecipitation (IP)–tandem mass spectrometry (LC-MS/MS)
experiments and reciprocal BLAST, we conducted a fly-human cross-species comparison of …

Protein Domain Co-occurrence Network (DCN) is a biological network that has not been
fully-studied. We analyzed the properties of the DCNs of H. sapiens, S. cerevisiae, C …

Multi-label classification refers to learning tasks with each instance belonging to one or more
classes simultaneously. It arose from real-world applications such as information retrieval …

Background Semantic similarity scores for protein pairs are widely applied in functional
genomic researches for finding functional clusters of proteins, predicting protein functions …