Latency and lytic replication in Epstein–Barr virus-associated oncogenesis

C Münz - Nature Reviews Microbiology, 2019 - nature.com
Epstein–Barr virus (EBV) was the first tumour virus identified in humans. The virus is
primarily associated with lymphomas and epithelial cell cancers. These tumours express …

Epstein–Barr virus latent genes

MS Kang, E Kieff - Experimental & molecular medicine, 2015 - nature.com
Abstract Latent Epstein–Barr virus (EBV) infection has a substantial role in causing many
human disorders. The persistence of these viral genomes in all malignant cells, yet with the …

The Epstein–Barr virus and the pathogenesis of lymphoma

M Vockerodt, LF Yap, C Shannon‐Lowe… - The Journal of …, 2015 - Wiley Online Library
Since the discovery in 1964 of the Epstein–Barr virus (EBV) in African Burkitt lymphoma, this
virus has been associated with a remarkably diverse range of cancer types. Because EBV …

Molecular mechanisms of EBV-driven cell cycle progression and oncogenesis

H Yin, J Qu, Q Peng, R Gan - Medical microbiology and immunology, 2019 - Springer
The early stage of oncogenesis is linked to the disorder of the cell cycle. Abnormal gene
expression often leads to cell cycle disorders, resulting in malignant transformation of …

[HTML][HTML] Epstein Barr virus associated lymphomas and epithelia cancers in humans

R Ayee, MEO Ofori, E Wright, O Quaye - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Epstein Barr virus (EBV) is a cosmopolitan oncogenic virus, infecting about 90% of the
world's population and it is associated to tumors originating from both epithelia and …

Epstein-Barr virus oncoprotein super-enhancers control B cell growth

H Zhou, SCS Schmidt, S Jiang, B Willox, K Bernhardt… - Cell host & …, 2015 - cell.com
Super-enhancers are clusters of gene-regulatory sites bound by multiple transcription
factors that govern cell transcription, development, phenotype, and oncogenesis. By …

Mechanisms of B-cell oncogenesis induced by Epstein-Barr virus

A Saha, ES Robertson - Journal of Virology, 2019 - Am Soc Microbiol
Epstein-Barr virus (EBV) is a ubiquitous gammaherpesvirus which asymptomatically infects
the majority of the world population. Under immunocompromised conditions, EBV can …

Cancers associated with human gammaherpesviruses

KW Wen, L Wang, JR Menke, B Damania - The FEBS journal, 2022 - Wiley Online Library
Epstein–Barr virus (EBV; human herpesvirus 4; HHV‐4) and Kaposi sarcoma‐associated
herpesvirus (KSHV; human herpesvirus 8; HHV‐8) are human gammaherpesviruses that …

Epstein–Barr virus infection as an epigenetic driver of tumorigenesis

A Kaneda, K Matsusaka, H Aburatani, M Fukayama - Cancer research, 2012 - AACR
Epstein–Barr virus (EBV) establishes latent infection and is associated with tumors, such as
Burkitt lymphoma, nasopharyngeal carcinoma, and gastric cancers. We recently reported …

Epstein–Barr virus-associated malignancies: Roles of viral oncoproteins in carcinogenesis

A El-Sharkawy, L Al Zaidan, A Malki - Frontiers in oncology, 2018 - frontiersin.org
The Epstein–Barr virus (EBV) is the first herpesvirus identified to be associated with human
cancers known to infect the majority of the world population. EBV-associated malignancies …