The identification of the first mobile colistin resistance (MCR) gene, mcr-1, in 2015 triggered
a rash of mcr screening reports. Subsequently, nine MCR-family genes and their variants …

Antimicrobial resistance (AMR) poses a serious threat to human, animal and environmental
health worldwide. Colistin has regained importance as a last-resort treatment against multi …

Background Following the discovery and emergence of the plasmid-mediated colistin
resistance gene, mcr-1, the Chinese government formally banned colistin as an animal …

Colistin has become the last-line antimicrobial for the treatment of multidrug resistant (MDR)
Enterobacterales in human medicine. To date, several colistin resistance genes have been …

A mobile colistin resistance gene mcr was first reported in 2016 in China and has since
been found with increasing prevalence across South-East Asia. Here we survey the …

Colistin is the last line of defense for the treatment of multidrug-resistant gram-negative
bacterial infections. However, colistin resistance is gradually increasing worldwide, with …

Antibiotic resistance is a current problem that significantly impacts overall health. The
dissemination of antibiotic resistance genes (ARGs) to urban areas primarily occurs through …

Antibacterial resistance is one of the 2019 World Health Organization's top ten threats to
public health worldwide. Hence, the emergence of β-lactam and colistin resistance among …

Resistance to colistin generated by the mcr-1 gene in Enterobacteriaceae is of great
concern due to its efficient worldwide spread. Despite the fact that the Lima region has a …

The mcr-type gene encodes the main plasmid-mediated mechanism of colistin resistance
and has been reported in several bacterial species obtained from different sources …